Results 171 to 180 of about 69,182 (204)

Coxsackievirus B3 modulates cardiac ion channels

The FASEB Journal, 2013
Infections with coxsackieviruses of type B (CVBs), which are known to induce severe forms of acute and chronic myocarditis, are often accompanied by ventricular arrhythmias and sudden cardiac death. The mechanisms underlying the development of virus‐induced, life‐threatening arrhythmias, which are pheno‐typically similar to those ...
Katja, Steinke, Frank, Sachse, Nicole, Ettischer, Nathalie, Strutz-Seebohm, Ulrike, Henrion, Matthias, Rohrbeck, Rafael, Klosowski, Dirk, Wolters, Stefan, Brunner, Wolfgang-Michael, Franz, Lutz, Pott, Carlos, Munoz, Reinhard, Kandolf, Eric, Schulze-Bahr, Florian, Lang, Karin, Klingel, Guiscard, Seebohm   +16 more
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Coxsackievirus B3 clinical isolates and murine myocarditis

Virus Research, 1996
Fifteen clinical coxsackievirus B3 (CVB3) isolates were assessed for cardiopathologic capabilities in adolescent male CD-1 mice in comparison to two well characterized cardiovirulent CVB3 strains. One isolate was cardiovirulent, one minimally cardiovirulent and the remaining 13 isolates were noncardiovirulent.
C J, Gauntt, M A, Pallansch
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Colchicine aggravates coxsackievirus B3 infection in mice

International Journal of Cardiology, 2016
There is a clinical need for immunosuppressive therapy that can treat myocarditis patients in the presence of an active viral infection. In this study we therefore investigated the effects of colchicine, an immunosuppressive drug which has been used successfully as treatment for pericarditis patients, in a mouse model of coxsackievirus B3(CVB3)-induced
Smilde, Bernard J., Woudstra, Linde, Fong Hing, Gene, Wouters, Diana, Zeerleder, Sacha, Murk, Jean-Luc, van Ham, Marieke, Heymans, Stephane, Juffermans, Lynda J. M., van Rossum, Albert C., Niessen, Hans W. M., Krijnen, Paul A. J., Emmens, Reindert W.   +12 more
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Host Immune Responses to Coxsackievirus B3

2008
Group B coxsackieviruses are members of the picornavirus family of small nonenveloped RNA viruses and have been associated with diseases of multiple organs including the heart, acinar and islet pancreas, liver, skeletal muscle, central nervous system, and testes. Damage to tissues occurs not only from the direct virus replication and infection of cells,
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Outbreak of herpangina associated with coxsackievirus B3 infection

The Pediatric Infectious Disease Journal, 1989
An outbreak of acute febrile illness was observed in summer, 1987, in a welfare home in which 31 healthy infants were accommodated. Within a 5-day period 25 infants (81%) acquired a febrile illness. Coxsackievirus B3 was isolated from 16 (64%) of 25 throat swabs.
T, Nakayama, T, Urano, M, Osano, Y, Hayashi, S, Sekine, T, Ando, S, Makinom   +6 more
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Role of MIP-2 in Coxsackievirus B3 Myocarditis

Journal of Molecular and Cellular Cardiology, 2000
Interleukin-8 (IL-8) is a chemotactic cytokine for neutrophils and lymphocytes. Macrophage inflammatory protein-2 (MIP-2) is a murine counterpart of IL-8. The present study was performed to determine the role of MIP-2 in murine myocarditis. We examined (1) the MIP-2 producing activity of Coxsackievirus B3 (CB3)-infected cultured macrophages, (2) serial
C, Kishimoto, H, Kawamata, S, Sakai, H, Shinohara, H, Ochiai   +4 more
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Extracellular Matrix Remodeling in Coxsackievirus B3 Myocarditis

Clinical Immunology and Immunopathology, 1997
The connective tissue abnormality in relation to T lymphocytes was investigated in murine myocarditis. Inbred BALB/c-nu/+ (euthymic and normal T cell function) and BALB/c-nu/nu (athymic and T cell deficient) mice were inoculated with coxsackievirus B3 (CB3). Hearts were stained with hematoxylin-eosin, Malloryazan, and silver impregnation, for reticulin
C, Kishimoto, M, Kitazawa, Y, Hiraoka, H, Takada   +3 more
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Intracardiac thrombus in murine coxsackievirus B3 myocarditis

Heart and Vessels, 1992
We studied the appearance of intracardiac mural thrombi with time and the relationship between thrombosis and congestive heart failure (CHF) in murine coxsackievirus B3 (CB3) myocarditis. Four- to six-week-old C3H/He mice were inoculated intraperitoneally with CB3 and were observed for 90 days.
C, Kishimoto, H, Ochiai, S, Sasayama
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Cardiomyocyte apoptosis in experimental coxsackievirus B3 myocarditis

Cardiovascular Pathology, 2003
Viruses are known to induce apoptosis in their host cells. We studied whether cardiomyocyte apoptosis occurs upon coxsackievirus B3 (CVB3) infection and whether virus-associated apoptosis plays a role in the pathogenesis of experimental myocarditis.BALB/c mice were infected with two variants of CVB3 causing either mild or severe myocarditis. Myocardial
Antti, Saraste, Anita, Arola, Tytti, Vuorinen, Ville, Kytö, Markku, Kallajoki, Kari, Pulkki, Liisa-Maria, Voipio-Pulkki, Timo, Hyypiä   +7 more
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Nucleotide differences of coxsackievirus B3 and chronic myocarditis

Heart and Vessels, 2014
The in vivo mechanisms in chronic myocarditis remain unclear. The aim of the current study was to clarify the genomic difference of amyocarditic (CB3O) and myocarditic (CB3M) coxsackievirus B3 (CB3) and the pathogenesis of in vivo mechanisms in chronic myocarditis.
Chiharu, Kishimoto, Nami, Takamatsu, Hiroshi, Ochiai, Kagemasa, Kuribayashi   +3 more
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