Results 21 to 30 of about 16,684 (160)

Interactions between enteroviruses and the host : implications for type 1 diabetes [PDF]

, 2014
Type 1 diabetes (T1D) is a disease that results after a selective destruction of the insulin-producing β-cells in the pancreas. The lack of β-cells renders T1D patients completely unable to synthesize and secrete insulin, which leads to a life-long ...
Larsson, Pär
core   +1 more source

The Role of B Lymphocytes in Coxsackievirus B3 Infection [PDF]

The American Journal of Pathology, 1999
Coxsackieviruses are important human pathogens, frequently causing myocarditis, pancreatitis, and a variety of less severe diseases. B lymphocytes appear central to the interaction between these viruses and their mammalian hosts, because agammaglobulinemic humans, genetically incapable of antibody production, are susceptible to chronic infections by ...
J. Lindsay Whitton, Christopher M. Perry, Stephanie Harkins, Ignacio Mena, John R. Gebhard, Fernando Rodriguez   +5 more
openaire   +3 more sources

Reflectance confocal microscopy for the diagnosis of skin infections and infestations [PDF]

, 2020
Reflectance confocal microscopy (RCM) is a noninvasive real-time imaging technique that has been widely used for the diagnosis of skin cancer. More recently, it has been reported as a useful tool for the diagnosis and management of several inflammatory ...
Arzberger, Edith, Bastos, Pedro Mendes, Ferreira, João, Leal-Filipe, Paulo, Oliveira, André Laureano, Pimenta, Rita, Soares-de-Almeida, Luís   +6 more
core  

Recurrent Coxsackievirus Infection in a Patient with Lamellar Ichthyosis [PDF]

Pediatric Dermatology, 2016
AbstractWe describe a case of coxsackievirus (CV) A6 infection in a patient with lamellar ichthyosis followed by subsequent CV A8 infection within the same year. Atypical cutaneous features characterized the infection. This observation, combined with the rapidity with which reinfection occurred, suggests that the natural history of CV infection may be ...
Leonard M. Milstone, Brittany G. Craiglow, Jonathan S. Leventhal, Matthew D. Vesely, William Damsky, Keith A. Choate, David Khalil   +6 more
openaire   +3 more sources

Hand, foot and mouth disease in Guangdong, China, in 2013: new trends in the continuing epidemic [PDF]

, 2014
Millions of incidents of hand, foot and mouth disease occur annually in China, with EVA71 and CVA16 as two major causative pathogens. A provincial surveillance system has been implemented in Guangdong for almost 5 years to analyze the aetiological ...
Guo, X., Ke, C., Li, H., Lin, J., Liu, L., Lu, J., Sun, L., Tan, X., Yi, L., Zeng, H., Zheng, H.   +10 more
core   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

Hand, foot and mouth disease in an immunocompetent adult due to Coxsackievirus A6 [PDF]

, 2013
Hand, foot and mouth disease most commonly occurs in children less than 10 years old, but can occur in immunocompetent adults. We describe a 37-year-old immunocompetent man who presented with multiple painful papules and vesicles on his palms and feet ...
Chan, C. Y., Chan, Kwokhung, Hung, Ivan F N, Shea, Yat Fung   +3 more
core   +1 more source

Rapid Diagnostic Testing for Infective Endocarditis and Myocarditis Using Nanopore Targeted Sequencing

iLABMED, EarlyView.
This research presents a method based on nanopore targeted sequencing (NTS) with pathogen‐specific panels for testing infective endocarditis (IE) and myocarditis. The NTS achieved a detection limit of 20 copies/test for the IE target panel and 10 copies/test for the myocarditis target panel.
Aisi Fu, Xian Wang, Zhiyong Shen, Jiashuang Gu, Ting Zhang, Feiyan Wang, Shiyu Jia, Linmei Yang, Feng Li, Jie Geng, Jun Cheng   +10 more
wiley   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, EarlyView.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Molecular determinants for virulence in coxsackievirus B1 infection [PDF]

Journal of Virology, 1997
Studies demonstrated that a strain derived from an infectious clone of coxsackievirus B1 (CVB1N) (N. Iizuka, H. Yonekawa, and A. Nomoto, J. Virol. 65:4867-4873, 1991) was 3 to 4 log10 less virulent than the myotropic Tucson strain of CVB1 (CVB1T) following intraperitoneal inoculation of newborn mice. Replacement of nucleotides (nt) 69 to 804 from the 5'
R M Gómez, Raymond P. Roos, J E Rinehart   +2 more
openaire   +3 more sources