Results 91 to 100 of about 152,781 (323)

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

open access: yesAdvanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf   +7 more
wiley   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

open access: yesAdvanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu   +7 more
wiley   +1 more source

Transcriptome of sessile serrated adenoma/polyps is associated with MSI‐high colorectal cancer and decreased expression of CDX2

open access: yesCancer Medicine, Volume 11, Issue 24, Page 5066-5078, December 2022., 2022
SSA/Ps showed characteristic gene expression with a strong resemblance to microsatellite instability‐high colorectal cancer. And the downregulation of CDX2 expression is an essential molecular mechanism involved in the initial stage of SSA/P tumorigenesis.
Daisuke Ohki   +12 more
wiley   +1 more source

Induction of Robust Immune Responses by CpG-ODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens

open access: yesInternational Journal of Nanomedicine, 2020
Shu-Yi Lin,1 Bing-Yu Yao,2 Che-Ming Jack Hu,2,3 Hui-Wen Chen1,3 1Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; 3Research Center for Nanotechnology and ...
Lin SY, Yao BY, Hu CMJ, Chen HW
doaj  

Establishment of Clinical Policy Making in Iran [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2014
The worldwide increase in the cost of health services has now become a shared concern for all health managers and experts. Regarding the limited allocatable resources to hygiene and treatment systems and numerous needs in this section, both the ...
Shirvani A   +3 more
doaj  

A core-based XRF scanning workflow for continuous measurement of mineralogical variations in clastic reservoirs

open access: yesMethodsX, 2022
Clastic reservoir core is routinely characterized using conventional, destructive spot sampling techniques. Whilst spot sampling provides useful textural and compositional information, the samples are typically widely spaced (∼ 25 cm), and hence ...
Arif Hussain, Khalid Al-Ramadan
doaj  

Pan‐Variant SARS‐CoV‐2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes

open access: yesAdvanced Science, EarlyView.
An integrative approach identifies conserved B‐cell and T‐cell epitopes within SARS‐CoV‐2 proteins, redirecting immune responses from variable to conserved regions. These epitopes elicit robust humoral and cellular immunity, neutralizing diverse viral variants. Promiscuous T‐cell epitopes demonstrate cross‐species efficacy, highlighting their potential
Masaud Shah   +5 more
wiley   +1 more source

Topology of Central Pattern Generators: Selection by Chaotic Neurons [PDF]

open access: yesarXiv, 1999
Central Pattern Generators (CPGs) in invertebrates are comprised of networks of neurons in which every neuron has reciprocal connections to other members of the CPG. This is a ``closed'' network topology. An ``open'' topology, where one or more neurons receives input but does not send output to other member neurons, is not found in these CPGs.
arxiv  

An Astrocyte-Modulated Neuromorphic Central Pattern Generator for Hexapod Robot Locomotion on Intel's Loihi [PDF]

open access: yesarXiv, 2020
Locomotion is a crucial challenge for legged robots that is addressed "effortlessly" by biological networks abundant in nature, named central pattern generators (CPG). The multitude of CPG network models that have so far become biomimetic robotic controllers is not applicable to the emerging neuromorphic hardware, depriving mobile robots of a robust ...
arxiv  

Toward robust phase-locking in Melibe swim central pattern generator models [PDF]

open access: yes, 2013
Small groups of interneurons, abbreviated by CPG for central pattern generators, are arranged into neural networks to generate a variety of core bursting rhythms with specific phase-locked states, on distinct time scales, that govern vital motor behaviors in invertebrates such as chewing, swimming, etc.
arxiv   +1 more source

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