Results 171 to 180 of about 71,530 (247)

Maternal Chrono‐Nutrition and Placental DNA Methylation: The BiSC Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This is the first study to examine how the timing of a mother's meals during pregnancy relates to changes in placental DNA methylation, an epigenetic mark. We found that the timing of the last daily meal was most important. Some epigenetic changes were linked to genes involved in placental function and development, and the long‐term health consequences
Joana Llauradó‐Pont   +12 more
wiley   +1 more source

GatorST: A Versatile Contrastive Meta‐Learning Framework for Spatial Transcriptomic Data Analysis

open access: yesSmall Methods, Volume 10, Issue 9, 8 May 2026.
GatorST learns spatially informed embeddings for spatial transcriptomics by coupling two‐hop subgraph graph convolutions with cluster‐aware pseudo‐label supervision and episodic contrastive meta‐learning. The framework captures neighbor‐level topology and tissue‐wide expression semantics without heavy augmentations, delivering robust representations ...
Zhenhao Zhang   +5 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness. [PDF]

open access: yesNat Genet, 2021
Pachano T   +12 more
europepmc   +1 more source

Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

open access: yesCancer Science, Volume 117, Issue 5, Page 1223-1234, May 2026.
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa   +17 more
wiley   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

open access: yesJournal of Advanced Nursing, Volume 82, Issue 5, Page 4840-4875, May 2026.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Methylation Analysis of CpG Islands in Pineapple SERK1 Promoter. [PDF]

open access: yesGenes (Basel), 2020
Luan A, Chen C, Xie T, He J, He Y.
europepmc   +1 more source

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