Results 171 to 180 of about 47,629 (244)

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Histopathology, Volume 89, Issue 1, Page 98-109, July 2026.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli, M. Elisa Vink‐Börger, Nanette S. van Roermund, Gesina van Lijnschoten, Chantal C.H.J. Kuijpers, Nicole C.T. van Grieken, Matteo Fassan, Joep E. Ijspeert, Rachel S. van der Post, Iris D. Nagtegaal   +9 more
wiley   +1 more source

CpG-Islands as Markers for Liquid Biopsies of Cancer Patients. [PDF]

Cells, 2020
Sprang M, Paret C, Faber J.
europepmc   +1 more source

FcMAPK4‐phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression

Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2264-2284, July 2026.
In Ficus carica fruit, the MAP kinase FcMAPK4 phosphorylates the NAC transcription factor FcNOR, which cooperates with ethylene response factor FcERF5 to activate the pectin degradation gene FcPG12, thereby promoting rapid softening of fig fruit. ABSTRACT Rapid softening of fig (Ficus carica L.) fruit during ripening leads to extremely short shelf life;
Yuan Wang, Zhiyi Fan, Yining Wang, Alexander Vainstein, Yuexuan Qiu, Yinan Sun, Huiqin Ma   +6 more
wiley   +1 more source

Predicting the methylation status of CpG islands from read distribution biases. [PDF]

BMC Genomics
Abdullaev ET, Haridoss DA, Arndt PF.
europepmc   +1 more source

Methylation Analysis of CpG Islands in Pineapple SERK1 Promoter. [PDF]

Genes (Basel), 2020
Luan A, Chen C, Xie T, He J, He Y.
europepmc   +1 more source

Two Decades of DNA Methylation Shifts Reveal Epigenomic Responses to Environmental Change in Wild Salmo salar From Its Southernmost Populations

Molecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT Atlantic salmon (Salmo salar) populations have been declining across the North Atlantic, with southern populations, including those in rivers draining into the southwestern Bay of Biscay, showing some of the strongest impacts. These rivers mark the species' southernmost distribution limit and are highly vulnerable to global change stressors ...
Alvaro Gutierrez‐Rodriguez, Carmen Blanco‐Fernandez, Eva Garcia‐Vazquez, Gonzalo Machado‐Schiaffino   +3 more
wiley   +1 more source

DNA methylation in follicular lymphoma

, 2010
PhDFollicular Lymphoma (FL) is a common B cell Non-Hodgkin Lymphoma with a median survival of 8-10 years. Patients frequently undergo transformation to a more aggressive lymphoma and this is associated with drastically reduced survival.
Ó Riain, Ciarán Liam
core  

Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements. [PDF]

Proc Natl Acad Sci U S A
You JS, Pierce S, Liang G, Jones PA.
europepmc   +1 more source

Escape From X‐Chromosome Inactivation Enables Survival in a Male With an Unbalanced X;19 Translocation

Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.
This study examines a rare inherited unbalanced X;19 translocation in a male proband and shows that silencing of the translocated chromosome 19 segment is incomplete. Allele‐specific expression analysis indicates that several informative chromosome 19 genes escape silencing, helping preserve essential autosomal dosage and likely contributing to ...
Onur Emre Onat, Tayfun Ozcelik
wiley   +1 more source

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. [PDF]

Sci Adv, 2021
Stielow B, Zhou Y, Cao Y, Simon C, Pogoda HM, Jiang J, Ren Y, Phanor SK, Rohner I, Nist A, Stiewe T, Hammerschmidt M, Shi Y, Bulyk ML, Wang Z, Liefke R.   +15 more
europepmc   +1 more source