Results 161 to 170 of about 487,995 (250)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, Volume 13, Issue 51, 14 September 2026.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

MAGE genes encoding for embryonic development in cattle is mainly regulated by zinc finger transcription factor family and slightly by CpG Islands. [PDF]

BMC Genom Data, 2022
Abera B, Dinka H.
europepmc   +1 more source

CDO1 as a prognostic biomarker and therapeutic target in gastric cancer: Mechanistic insights into the PI3K/AKT‐THBS1 axis and epigenetic reactivation by decitabine

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CDO1 is a tumour suppressor in gastric cancer that directly binds PI3K p85α, disrupting p85α–p110α dimerization to inhibit the PI3K/AKT–THBS1 axis. Decitabine epigenetically restores CDO1 expression and exerts CDO1‐dependent anti‐tumour activity, synergizing with 5‐FU. Abstract Background As a pivotal metabolic enzyme, cysteine dioxygenase type 1 (CDO1)
Fazhi Wang, Runkai Zhou, Jinfeng Cai, Jiazhe Wen, Abudushalamu Yalikun, Yang Yu, Yugang Wen   +6 more
wiley   +1 more source

1:50,000 British Solomon Islands Protectorate [cartographic material] /

, 1971
1st ed. Geological map series of the Solomon Islands.; Relief shown by contours, spot heights, and formline drawings.; Includes geological timetable, cross sections, text, magnetic variation diagram, index to adjoining sheets, and insets.; Includes ...
Solomon Islands. Department of Geological Surveys.
core  

Pattools‑implemented methylation vector analysis reveals aberrant subtype‑specific methylation in lung cancer across tissue and plasma cfDNA

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. 115 tissue samples across five lung cancer subtypes and matched plasma cfDNA were profiled by WGBS. 2. Pattools implements methylation vector (MV) clustering to isolate tumour‐specific fragments from immune and cell‐origin signals in bulk BS‐seq. 3.
Zehua Dong, Yifeng Luo, Tingting Hu, Yihang Cheng, Qiaoling Ren, Li Xu, Yuan Tan, Wei Li, Yaoxiang Sun, Mingzhi Chen, Zhonghua Shen, Bin Zhang, Youhuang Bai, Yue Tao, Zhihong Cao, Deqiang Sun   +15 more
wiley   +1 more source

Understanding the Epigenetic Landscape of Barrett's Esophagus and Esophageal Cancer: A Review of Current Findings, Caveats and Future Directions

Genes, Chromosomes and Cancer, Volume 65, Issue 9, September 2026.
ABSTRACT Esophageal cancer (OC) is currently the eighth most common form of cancer worldwide with a 5‐year survival rate of 10%–20%, with the primary risk factor of esophageal adenocarcinoma (OAC) being the development of Barrett's Esophagus (BO).
Louise Lawless, Trevor Doherty, Carla Surlis, Niamh Gilmartin, Therese M. Murphy   +4 more
wiley   +1 more source

Investigating the role of CpG islands and DNA methylation at 3'UTRs in cancer. [PDF]

Life Sci Alliance
Wilson C, Kanhere A.
europepmc   +1 more source

DNA Methylation of Human Choline Kinase Alpha Promoter-Associated CpG Islands in MCF-7 Cells. [PDF]

Genes (Basel), 2021
Mohamed Sa'dom SAF, Raikundalia S, Shamsuddin S, See Too WC, Few LL.   +4 more
europepmc   +1 more source

Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Schematic overview of the pathways and pathological mechanisms connecting atmospheric aerosol exposure to PD. Atmospheric aerosols, including PM2.5 and nanometer/ultrafine particles loaded with metal particles, persistent organic pollutants (POPs), polycyclic aromatic hydrocarbons (PAHs) and dioxins, enter the body predominantly via pulmonary ...
Yitian Gao, Minxiang Dong, Chenyang Duan, Xiaohan Zheng, Liming Qu   +4 more
wiley   +1 more source

CpG islands search in DNA sequences

, 2015
This thesis focuses on searching for CpG islands of DNA sequences based on analysis of DNA spectrograms. The first part is theoretical and deals with the significance CpG island, and a description of the algorithms that are used or have been proposed for
Nerušil, Václav
core   +1 more source