Results 201 to 210 of about 47,629 (244)
Developmental features of DNA methylation in CpG islands of human gametes and preimplantation embryos. [PDF]
Exp Ther Med, 2019 Huang Y +7 more
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CpG Islands in Human X‐Inactivation
Annals of Human Genetics, 2003 SummarySequence comparison analyses have been carried out for 19 genes escaping X‐inactivation versus 73 genes subject to X‐inactivation, and 100 randomly chosen X chromosome genes versus 100 randomly chosen autosomal genes. The coding sequence of the genes and their upstream and downstream flanking sequences were investigated using a series of windows
Ke, X., Collins, A.
core +6 more sources
Tandem repeats in the CpG islands of imprinted genes
Genomics, 2006 In contrast to most genes in mammalian genomes, imprinted genes are monoallelically expressed depending on the parental origin of the alleles. Imprinted gene expression is regulated by distinct DNA elements that exhibit allele-specific epigenetic ...
Barbara Hutter +2 more
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Current Opinion in Genetics & Development, 1995
Of the estimated 45,000 CpG islands in the human genome, the overwhelming majority are found at the 5' ends of genes and their identification and cloning are proving very useful for finding and isolating genes. Recent work has shed light on the chromosomal distribution and origin of CpG islands.
S H, Cross, A P, Bird
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Of the estimated 45,000 CpG islands in the human genome, the overwhelming majority are found at the 5' ends of genes and their identification and cloning are proving very useful for finding and isolating genes. Recent work has shed light on the chromosomal distribution and origin of CpG islands.
S H, Cross, A P, Bird
openaire +2 more sources
The length of CpG islands is associated with the distribution of Alu and L1 retroelements
Genomics, 2006 Alu and L1 retroelements have been suggested to initiate the spread of CpG methylation. In this study, the spread of CpG methylation was estimated based on the distance between the CpG islands and the nearest retroelements.
Mun-Gan Rhyu +2 more
exaly +2 more sources
Primate CpG Islands Are Maintained by Heterogeneous Evolutionary Regimes Involving Minimal Selection
Cell, 2011 SummaryMammalian CpG islands are key epigenomic elements that were first characterized experimentally as genomic fractions with low levels of DNA methylation. Currently, CpG islands are defined based on their genomic sequences alone.
Netta Mendelson Cohen, Amos Tanay
exaly +2 more sources
Epigenomics: beyond CpG islands
Nature Reviews Genetics, 2004Epigenomic studies aim to define the location and nature of the genomic sequences that are epigenetically modified. Much progress has been made towards whole-genome epigenetic profiling using molecular techniques, but the analysis of such large and complex data sets is far from trivial given the correlated nature of sequence and functional ...
Melissa J, Fazzari, John M, Greally
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CpG Islands in vertebrate genomes
Journal of Molecular Biology, 1987Although vertebrate DNA is generally depleted in the dinucleotide CpG, it has recently been shown that some vertebrate genes contain CpG islands, regions of DNA with a high G+C content and a high frequency of CpG dinucleotides relative to the bulk genome.
M, Gardiner-Garden, M, Frommer
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