Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides [PDF]
PLoS ONE, 2008 While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Dan, Jennifer M. +3 more
core +16 more sources
Role of Interleukin-6 in the Antigen-Specific Mucosal Immunoglobulin A Responses Induced by CpG Oligodeoxynucleotide-Loaded Cationic Liposomes. [PDF]
Membranes (Basel), 2022 Tada R +6 more
europepmc +3 more sources
Neonate Intestinal Immune Response to CpG Oligodeoxynucleotide Stimulation [PDF]
PLoS ONE, 2009 The development of mucosal vaccines is crucial to efficiently control infectious agents for which mucosae are the primary site of entry. Major drawbacks of these protective strategies are the lack of effective mucosal adjuvant. Synthetic oligodeoxynucleotides that contain several unmethylated cytosine-guanine dinucleotide (CpG-ODN) motifs are now ...
Lacroix-Lamandé, Sonia +5 more
openaire +6 more sources
Ferumoxytol and CpG oligodeoxynucleotide 2395 synergistically enhance antitumor activity of macrophages against NSCLC with EGFRL858R/T790M mutation. [PDF]
Int J Nanomedicine, 2019 Wang G +6 more
europepmc +3 more sources
Mannose-Modified Liposome Co-Delivery of Human Papillomavirus Type 16 E7 Peptide and CpG Oligodeoxynucleotide Adjuvant Enhances Antitumor Activity Against Established Large TC-1 Grafted Tumors in Mice. [PDF]
Int J Nanomedicine, 2020 Zhao Y +8 more
europepmc +3 more sources
Effects of CpG- oligodeoxynucleotides on dendritic cell development [PDF]
Nucleic Acids Symposium Series, 2008 Dendritic cell (DC) development begins in the bone marrow and immature progenitors reach their sites of residence in lymphoid organs. The mechanism of DC development in the bone marrow and in peripheral lymphoid organs is poorly understood. Here, we examined the effects of synthetic oligodeoxynucleotides containing a CpG motif (CpG-ODNs) on the ...
Ryuji Ohue‐Kitano +2 more
openalex +3 more sources
Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner. [PDF]
Life (Basel)A CpG oligodeoxynucleotide (CpG-ODN), iSN40, was originally identified as promoting the mineralization and differentiation of osteoblasts, independent of Toll-like receptor 9 (TLR9).
Ikeda R +5 more
europepmc +2 more sources
Intracellular Cleavable CpG Oligodeoxynucleotide-Antigen Conjugate Enhances Anti-tumor Immunity. [PDF]
Mol Ther, 2017 Kramer K +4 more
europepmc +3 more sources
Медицинская иммунология, 2015 This study presents data upon the effects of CpG oligonucleotide substance (CpG ODN 2006). The commercial preparation was applied in vitro as a single agent, or in combination with various cytokine production inducers.
S. N. Klyueva +2 more
openalex +4 more sources