Results 101 to 110 of about 9,596 (243)

From bench to bedside [PDF]

, 2015
The adaptive immune system has been the main focus of immunological strategies in oncology with only more recent approaches targeting innate immunity.
Scheithauer, Werner, Schmidt, Manuel, Schmoll, Hans-Joachim, Wittig, Burghardt   +3 more
core   +1 more source

Immunomodulatory asthma therapy in the equine animal model: A dose‐response study and evaluation of a long‐term effect [PDF]

, 2019
Introduction Equine asthma represents a naturally occurring animal model for human allergic neutrophilic asthma. Inhalative nanoparticle‐bound cytosine‐phosphate‐guanosine (CpG‐GNP) immunotherapy, independent of specific allergens, has already shown ...
Bartl, Carolin, Geh, Katharina J., Gehlen, Heidrun, Geuder, Sabine, Goehring, Lutz S., Klier, John, Reese, Sven, Winter, Gerhard   +7 more
core   +1 more source

Supplementary Figure 1 from Therapeutic Administration of a Synthetic CpG Oligodeoxynucleotide Triggers Formation of Anti-CpG Antibodies

, 2023
Julia Karbach, Antje Neumann, Claudia Wahle, Kathrin Brand, Sacha Gnjatic, Elke Jäger   +5 more
openalex   +1 more source

CpG Oligodeoxynucleotides Enhance the Efficacy of Adoptive Cell Transfer Using Tumor Infiltrating Lymphocytes by Modifying the Th1 Polarization and Local Infiltration of Th17 Cells [PDF]

, 2010
Adoptive cell transfer immunotherapy using tumor infiltrating lymphocytes (TILs) was an important therapeutic strategy against tumors. But the efficacy remains limited and development of new strategies is urgent.
Chunhong Wang, Lin Xu, Tao Ren, Ya Zhou, Yongjie Liang, Zengguang Xu, Zhenke Wen, Zhongmin Liu   +7 more
core   +2 more sources

Interferon-α/β receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006

BMC Immunology, 2003
Background Oligodeoxynucleotides containing unmethylated CpG motifs (CpG ODN) are known to exert a strong adjuvant effect on Th1 immune responses. Although several genes have been reported, no comprehensive study of the gene expression profiles in human ...
Wakiguchi Hiroshi, Imai Shosuke, Hashimoto Noriko, Batchelor Jonathan, Homma Toshiki, Kato Atsushi, Saito Hirohisa, Matsumoto Kenji   +7 more
doaj   +1 more source

Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD11. [PDF]

J Poult Sci, 2023
Ichikawa K, Matsuzaki M, Ezaki R, Horiuchi H, Yamamoto Y.   +4 more
europepmc   +1 more source

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
A Biancotto, A Boasso, A Boasso, A Chahroudi, A Pichlmair, Amanda P. Smith, AR Sedaghat, AS Beignon, AW Hardy, B Jacquelin, B Malleret, C Guiducci, C Hirotsu, C Kornfeld, C Pasare, CA Dutertre, Cristiana Guiducci, D Favre, D Hackl, Daniel Normolle, DE Levy, DJ Shedlock, DK Monteith, DK Monteith, DL Sodora, Elizabeth R. Wonderlich, ER Wonderlich, FJ Barrat, FJ Barrat, Franck J. Barrat, G Silvestri, Guido Silvestri, I Pandrea, IV Pandrea, J Estaquier, JA Phillips, JA Tavel, JD Estes, JD Estes, JD Estes, JM Brenchley, JM Orendi, JN Mandl, JP Herbeuval, JP Herbeuval, K Honda, KD Mir, KN Brown, KN Brown, KN Brown, L Campillo-Gimenez, LD Harris, LJ Picker, M Manion, M Murphey-Corb, M Nascimbeni, M O'Brien, M Ries, M Swiecki, MP Longhi, Muhamuda Kader, N Sachsenberg, NL Letvin, P Fitzgerald-Bocarsly, PD Katsikis, R Ellegard, RK Reeves, RS Geary, RS Geary, S Feldman, S Fiorentini, S Kwa, S Lederer, SE Bosinger, SE Bosinger, Simon C. Watkins, Simon M. Barratt-Boyes, TH Vanderford, V Monceaux, V Soumelis   +79 more
core   +3 more sources

Sustained delivery of CpG oligodeoxynucleotide by acetalated dextran microparticles augments effector response to Computationally Optimized Broadly Reactive Antigen (COBRA) influenza hemagglutinin. [PDF]

Int J Pharm, 2023
Batty CJ, Amouzougan EA, A Carlock M, Ross TM, Bachelder EM, Ainslie KM.   +5 more
europepmc   +1 more source

The role of TLR2, TLR4, and TLR9 in the pathogenesis of atherosclerosis [PDF]

, 2016
Toll-like receptors (TLRs) are key players in the pathogenesis of inflammatory conditions including coronary arterial disease (CAD). They are expressed by a variety of immune cells where they recognize pathogen-associated molecular patterns (PAMPs). TLRs
Pace, Nikolai Paul, Roshan, Mohsin H. K, Tambo, Amos   +2 more
core   +4 more sources

Endosomal Translocation of CpG-Oligodeoxynucleotides Inhibits DNA-PKcs-Dependent IL-10 Production in Macrophages [PDF]

, 2008
Satoshi Yotsumoto, Kazuharu Saegusa, Yukihiko Aramaki   +2 more
openalex   +1 more source