Results 121 to 130 of about 9,596 (243)
CpG Oligodeoxynucleotide Developed to Activate Primate Immune Responses Promotes Antitumoral Effects in Combination with a Neoantigen-Based mRNA Cancer Vaccine. [PDF]
Drug Des Devel Ther, 2021 Li Q, Ren J, Liu W, Jiang G, Hu R.
europepmc +1 more source
Structural and functional characterisation of the Toll like receptor 9 of Aotus nancymaae , a non-human primate model for malaria vaccine development [PDF]
, 2018 In the absence of suitable rodent animal models for Plasmodium falciparum malaria, the efficacy testing of asexual blood-stage vaccine candidates in Aotus nancymaae represents a tool to select between different formulations before conducting expensive ...
Daubenberger, Claudia +4 more
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Advanced ScienceAggressive nature of colon cancer and current imprecise therapeutic scenarios simulate the development of precise and effective treatment strategies. To achieve this, a tumor environment‐activated photosensitized biomimetic nanoplatform (PEG2000‐SiNcTI ...
Mengmeng Xiong +11 more
doaj +1 more source
CpG-Based Nanovaccines for Cancer Immunotherapy
International Journal of Nanomedicine, 2021 Wenqiang Chen,1 Mingxia Jiang,1 Wenjing Yu,1 Zhiwei Xu,1 Xinyue Liu,1 Qingmiao Jia,1 Xiuwen Guan,1– 3 Weifen Zhang1– 3 1College of Pharmacy, Weifang Medical University, Weifang, 261053, People’s Republic of China; 2Collaborative Innovation Center for ...
Chen W +7 more
doaj
JCI InsightRadiation therapy (RT) is frequently used to treat cancers, including soft-tissue sarcomas. Prior studies established that the toll-like receptor 9 (TLR9) agonist cytosine-phosphate-guanine oligodeoxynucleotide (CpG) enhances the response to RT in ...
Chang Su +20 more
doaj +1 more source
OncoImmunology, 2018 Toll-Like Receptor 9 (TLR9) stimulation selectively triggers the formation of a cell cluster termed intrahepatic myeloid aggregation for T cell expansion” (iMATE) in a mouse chronic viral hepatitis model.
Yung-Chang Lin +12 more
doaj +1 more source
CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses [PDF]
, 2017 Da‐Wei Yeh +9 more
openalex +1 more source
Scientific ReportsAntisense oligonucleotides (ASOs) are synthetic single-stranded oligonucleotides that bind to RNAs through Watson–Crick base pairings. They are actively being developed as therapeutics for various human diseases.
Tokuyuki Yoshida +12 more
doaj +1 more source
CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells [PDF]
, 2018 BTLA (B- and T-lymphocyte attenuator) is a prominent co-receptor that is structurally and functionally related to CTLA-4 and PD-1. In T cells, BTLA inhibits TCR-mediated activation.
Derré, Laurent +7 more
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