Results 51 to 60 of about 5,254 (231)

INFLUENCE OF CpG ODN 2006 OLIGODEOXYNUCLEOTIDE ON CYTOKINE PRODUCTION BY BLOOD CELLS OF HUMANS VACCINATED AGAINST PLAGUE

open access: yesМедицинская иммунология, 2015
This study presents data upon the effects of CpG oligonucleotide substance (CpG ODN 2006). The commercial preparation was applied in vitro as a single agent, or in combination with various cytokine production inducers.
S. N. Klyueva   +2 more
doaj   +1 more source

CpG Adjuvant in Allergen-Specific Immunotherapy: Finding the Sweet Spot for the Induction of Immune Tolerance

open access: yesFrontiers in Immunology, 2021
Prevalence and incidence of IgE-mediated allergic diseases have increased over the past years in developed and developing countries. Allergen-specific immunotherapy (AIT) is currently the only curative treatment available for allergic diseases that has ...
Guillem Montamat   +6 more
doaj   +1 more source

Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α

open access: yesInternational Journal of Nanomedicine, 2012
Yuvaraj Manoharan,1,* Qingmin Ji,2,* Tomohiko Yamazaki,2,3 Shanmugavel Chinnathambi,1 Song Chen,2,4 Ganesan Singaravelu,1 Jonathan P Hill,2 Katsuhiko Ariga,2,5 Nobutaka Hanagata3,6 1Department of Medical Physics, Anna University, Chennai, India ...
Manoharan Y   +8 more
doaj  

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

open access: yesExploration, EarlyView.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang   +15 more
wiley   +1 more source

Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities

open access: yesInternational Journal of Nanomedicine, 2017
Nobutaka Hanagata,1,2 Xianglan Li,1 Min-Hua Chen,1 Jie Li,1 Shinya Hattori1 1Nanotechnology Innovation Station, National Institute for Materials Science, Tsukuba, 2Graduate School of Life Science, Hokkaido University, Sapporo, Japan Abstract ...
Hanagata N   +4 more
doaj  

Engineered strategies for the allergic disease therapy

open access: yesInterdisciplinary Medicine, EarlyView.
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian   +4 more
wiley   +1 more source

CpG-DNA enhancement the immune elicited as adjuvant of foot- and- mouth disease vaccine

open access: yesArchives of Razi Institute, 2010
In the present study the effect of the locally produced genetic adjuvant of ginea pig specific CpG-motif-containing oligodeoxynucleotide (CpG-ODN) in an inactivated FMD virus vaccine was evaluated.
Morshedi, A.   +2 more
doaj  

B-Cell Lymphomas Differ in their Responsiveness to CpG Oligodeoxynucleotides [PDF]

open access: yesClinical Cancer Research, 2005
AbstractHuman B cells detect CpG motifs within microbial DNA via TLR9. Synthetic CpG oligodeoxynucleotides are currently being tested in clinical trials for the therapy of different types of B cell non-Hodgkin's lymphoma. However, there is only limited information on the CpG oligodeoxynucleotide sensitivity of primary malignant B cells of different non-
Bertold Emmerich   +11 more
openaire   +3 more sources

Review: CPG as a controller for biomimetic floating robots [PDF]

open access: yesarXiv, 2021
All vertebrates are capable of performing various types of physical activity. Locomotor patterns are created by the cyclical coordinated work of the skeletal muscles. The organization of such a system in living organisms is responsible for networks of interconnected populations of neurons capable of forming rhythmic activity - CPG.
arxiv  

Immunomodulatory Effects of CpG Oligodeoxynucleotides on Established Th2 Responses [PDF]

open access: yesClinical and Vaccine Immunology, 2002
ABSTRACTCpG oligodeoxynucleotides (CpG ODNs) are known to induce type 1 T-helper-cell (Th1) responses. We have previously demonstrated that CpG ODNs administered during sensitization prevent Th2-mediated eosinophilic airway inflammation in vivo. We also reported that key Th1 cytokines, gamma interferon (IFN-γ) and interleukin 12 (IL-12), are not ...
Vipul V. Jain   +4 more
openaire   +3 more sources

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