Results 81 to 90 of about 5,254 (231)

An Astrocyte-Modulated Neuromorphic Central Pattern Generator for Hexapod Robot Locomotion on Intel's Loihi [PDF]

open access: yesarXiv, 2020
Locomotion is a crucial challenge for legged robots that is addressed "effortlessly" by biological networks abundant in nature, named central pattern generators (CPG). The multitude of CPG network models that have so far become biomimetic robotic controllers is not applicable to the emerging neuromorphic hardware, depriving mobile robots of a robust ...
arxiv  

Toward robust phase-locking in Melibe swim central pattern generator models [PDF]

open access: yes, 2013
Small groups of interneurons, abbreviated by CPG for central pattern generators, are arranged into neural networks to generate a variety of core bursting rhythms with specific phase-locked states, on distinct time scales, that govern vital motor behaviors in invertebrates such as chewing, swimming, etc.
arxiv   +1 more source

Tissue‐Resident Memory CD8+ T Cells: Differentiation, Phenotypic Heterogeneity, Biological Function, Disease, and Therapy

open access: yesMedComm, Volume 6, Issue 3, March 2025.
Xu et al. described the differentiation, biological function, and phenotype heterogeneity of CD8+TRM cells across various types of tissues and distinct disease settings, and discussed their potential roles in the designation of vaccines against infectious diseases and immune therapy of tumors .
Luming Xu, Lilin Ye, Qizhao Huang
wiley   +1 more source

Finding Design Opportunities for Smartness in Consumer Packaged Goods [PDF]

open access: yesarXiv, 2019
This study attempts to understand the use of Consumer Packaged Goods (CPG) in practice to obtain insights to develop design interventions that bring the CPGs into the Internet of Things. Our ultimate aim is to equip CPGs with a layer of smartness so that CPGs could collect information about their use and provide extra services and functionalities. With
arxiv  

Obesity and the gut microbiota: implications of neuroendocrine and immune signaling

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1397-1420, March 2025.
An unhealthy diet impairs the symbiotic relationship between the gut microbiota and the host, contributing to obesity. At the intestinal level, identification of host–microbe events essential for proper neuroendocrine/immune signaling is key to the development of microbiome‐based strategies to promote metabolic health in obesity (probiotics ...
Marina Romaní‐Pérez   +6 more
wiley   +1 more source

CpG-coated prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma

open access: yesTranslational Oncology, 2020
High-risk neuroblastoma, which is associated with regional and systemic metastasis, is a leading cause of cancer-related mortality in children. Responding to this need for novel therapies for high-risk patients, we have developed a “nanoimmunotherapy ...
Juliana Cano-Mejia   +5 more
doaj  

Interferon-α/β receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006

open access: yesBMC Immunology, 2003
Background Oligodeoxynucleotides containing unmethylated CpG motifs (CpG ODN) are known to exert a strong adjuvant effect on Th1 immune responses. Although several genes have been reported, no comprehensive study of the gene expression profiles in human ...
Wakiguchi Hiroshi   +7 more
doaj   +1 more source

Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response

open access: yesRespiratory Research, 2009
Bacterial genome is characterized by frequent unmethylated cytosine-phosphate-guanine (CpG) motifs. Deleterious effects can occur when synthetic oligodeoxynucleotides (ODN) with unmethylated CpG dinucleotides (CpG-ODN) are administered in a systemic ...
Hasegawa Naoki   +10 more
doaj   +1 more source

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