Results 91 to 100 of about 1,475,288 (355)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A finite element strategy coupling a gradient-enhanced damage model and cohesive cracks for quasi-brittle materials [PDF]
, 2013 A new combined strategy to describe failure of quasi-brittle materials is presented thus allowing the complete description of the process, from initiation of damage to crack propagation.
Rodríguez Ferran, Antonio +1 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in Built Environment, 2020 Although many models for service life predictions have been developed, their application to existing bridges is still not at a satisfactory level. The here presented coupled three-dimensional chemo-hygro-thermo-mechanical (CHTM) model can realistically ...
Marija Kušter Marić +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Application of local and non-local approaches to multiple fatigue crack initiation and propagation [PDF]
, 2003 Fatigue strength conditions presented in terms of normalized equivalent stress functionals defined on loading processes are used to unite the stages of material damage with fatigue crack initiation and multiple crack propagation under arbitrary loading ...
Mikhailov, SE, Namestnikova, IV
core
Fracture toughness of a zirconia engineering ceramic and the effects thereon of surface processing with fibre laser radiation [PDF]
, 2010 Vickers hardness indentation tests were employed to investigate the near-surface changes in the hardness of a fibre laser-treated and an as-received ZrO2 engineering ceramic.
Lawrence, Jonathan +2 more
core +3 more sources
Image‐based concrete crack assessment using mask and region‐based convolutional neural network
Structural Control & Health Monitoring, 2019 Recently, many countries have investigated replacing conventional visual inspection with computer‐vision–based inspection to enhance the efficiency, speed, and objectivity of inspection. This paper presents a novel crack assessment framework for concrete
Byunghyun Kim, Soojin Cho
semanticscholar +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source