Results 91 to 100 of about 275,126 (317)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Crack growth resistance in nuclear graphite [PDF]

open access: yes, 2002
R-curve behaviour is often used for evaluating crack growth resistance in quasibrittle materials but few studies have focused on polycrystalline graphite. In this study, R-curve behaviour in three commercial grade nuclear graphites, of varying structure
Fazluddin, Shahed
core  

Fatigue crack growth in thin notched woven glass composites under tensile loading. Part I: experimental [PDF]

open access: yes, 2011
Helicopter blades are made of composite materials mainly loaded in fatigue and have normally relatively thin skins. A through-the-thickness crack could appear in these skins.
Barrau, Jean-Jacques   +7 more
core   +1 more source

J integral computation and limit load analysis of bonded composite repair in cracked pipes under pressure

open access: yesFracture and Structural Integrity, 2019
In this paper an additional criterion was introduced to evaluate the composite repair systems using the limit load analysis. The plastic collapse pressure of API 5L X65 PSL2 steel pressure vessel structure with crack defect is numerically investigated ...
M. Belhamiani   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Crack propagation in honeycomb cellular materials: a computational approach

open access: yes, 2012
Computational models based on the finite element method and linear or nonlinear fracture mechanics are herein proposed to study the mechanical response of functionally designed cellular components. It is demonstrated that, via a suitable tailoring of the
Paggi, M, Paggi, Marco, Marco Paggi
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Thermal effect of plastic dissipation at the crack tip on the stress intensity factor under cyclic loading [PDF]

open access: yes, 2011
The authors acknowledge Arts et Métiers ParisTech and Fondation Arts et Métiers for the financial support of Paul C. Paris’ stay at LAMEFIP in 2009. The encouragement of Prof. Ivan Iordanoff, Director of LAMEFIP, is acknowledged with thanks.
PARIS, Paul C.   +8 more
core   +1 more source

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