Results 81 to 90 of about 338,464 (293)
In this paper an additional criterion was introduced to evaluate the composite repair systems using the limit load analysis. The plastic collapse pressure of API 5L X65 PSL2 steel pressure vessel structure with crack defect is numerically investigated ...
M. Belhamiani +4 more
doaj +1 more source
This paper discusses information technology as political and practical discourse. This repetitive discursive model can be distinguished in global, regional and local contexts and contains an optimistic belief in technology as an independent power that automatically furthers democratic development.
Annelie Ekelin, Pirjo Elovaara
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Fatigue crack growth behaviour and life prediction for 2324-T39 and 7050-T7451 aluminium alloys under truncated load spectra [PDF]
This paper presents a study of crack growth behaviour in aluminium alloys 2324- T39 and 7050-T7451 subjected to flight-by-flight load spectra at different low- stress truncation levels. Crack branching was observed in the higher truncation levels for the
Bao, Rui, Zhang, Xiang
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Cracking the epitranscriptome [PDF]
Over 100 distinct chemical modifications can be catalyzed on RNA post-synthesis, potentially serving as a post-transcriptional regulatory layer of gene expression. This review focuses on recent advances, knowledge gaps, and challenges pertaining to N6-methyladenosine (m6A), an abundant modification of mRNA for which substantial progress has been made ...
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Fail-safe design of integral metallic aircraft structures reinforced by bonded crack retarders [PDF]
This paper presents an investigation on the effectiveness of crack growth retarders bonded to integral metallic structures. The study was performed by both numerical modelling and experimental tests.
Irving, Phil E. +9 more
core +1 more source
In this work the finite element method was used to analyse the composite patch shape effect of the repair performance. Unlike all the works done conducted so far in this domain, this work proposed here, takes into account the reducing both, the stress ...
Baghdadi Mohammed +4 more
doaj +1 more source

