Results 111 to 120 of about 1,475,288 (355)
Data in Brief, 2018 SDNET2018 is an annotated image dataset for training, validation, and benchmarking of artificial intelligence based crack detection algorithms for concrete.
S. Dorafshan, R. Thomas, Marc Maguire
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Fracture and Structural Integrity, 2019 In this work the finite element method was used to analyse the composite patch shape effect of the repair performance. Unlike all the works done conducted so far in this domain, this work proposed here, takes into account the reducing both, the stress ...
Baghdadi Mohammed +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The influence of cracks on the corrosion initiation time caused by chloride diffusion in concrete structures using the Boundary Element Method [PDF]
Revista IBRACON de Estruturas e MateriaisReinforced concrete structures in coastal zones are subject to corrosion triggered by chloride ions. In contact with the concrete surface, such ions penetrate through the material’s porous microstructure, mainly by diffusion, and accumulate on the ...
Vinícius de Barros Souza +1 more
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Effect of Crystallites Structure of PAN-based Carbon Fibers on Tensile Strength
Cailiao gongcheng, 2017 Carbon fiber is composed of crystallite and amorphous carbon. The X-ray diffraction (XRD) and Raman spectroscopy were used to investigate the influencing mechanism of the microstructure of crystallites of polyacrylonitrile (PAN)-based carbon fibers on ...
ZHONG Yun-jiao, BIAN Wen-feng
doaj +1 more source
3D numerical study of the transient behaviour on plasticity induced crack closure [PDF]
, 2019 Daniel Camas, Fernando Antunes, Pablo Lopez-Crespo, Antonio Gonzalez-Herrera, 3D Numerical Study of the Transient Behaviour on Plasticity Induced Crack Closure, Abstract Booklet of the MSMF9, Edited by Pavel Sandera, Brno University of Technology, 2019 ...
Antunes, Fernando +3 more
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