Results 71 to 80 of about 58,593 (304)

Numerical Model of Plastic Deformation on Cracked Surface under Repeated Pneumatic Impact

open access: yesAdvances in Materials Science and Engineering, 2018
Crack-closure treatment through repeated impact is supposed to be an effective, economical way to extend the fatigue remaining life for fatigue-affected structures with less damage.
Zhiyuan YuanZhou   +3 more
doaj   +1 more source

The effect of thickness on fatigue crack propagation in 7475-T731 aluminum alloy sheet [PDF]

open access: yes
Tests were conducted on three thicknesses of 7475-T731 aluminum alloy sheet to investigate the effect of thickness on fatigue crack propagation under constant amplitude loading conditions and on retardation following a single peak overload.
Daiuto, R. A., Hillberry, B. M.
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

RESEARCH ON FATIGUE CRACK PROPAGATION OF LEAF SPRING UNDER VARIABLE AMPLITUDE LOAD

open access: yesJixie qiangdu, 2021
The prediction model of leaf springs fatigue crack growth under variable amplitude loads is mainly Schütz phenomenological model. However, the effect of the crack closure effect on fatigue crack propagation and the relationship between the parameters and
XIANG YuXia, WU ZhiFei
doaj  

Fatigue crack propagation behavior of old puddle iron including crack closure effects

open access: yesProcedia Structural Integrity, 2016
AbstractIn this paper the fatigue crack growth behavior in structural components from the old 19th century structures (e.g. bridges) has been investigated. The delivered material for investigation was extracted from a beam made of puddled iron, commonly used in 19th century. The obtained results from several ancient railway metallic bridges (located in
Lesiuk, Grzegorz   +3 more
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Variables controlling fatigue crack growth of short cracks [PDF]

open access: yes
A study was conducted to evaluate the roles of crack closure and microstructure in the fatigue growth of short cracks. Testing was performed at R ratios of 0.1, 0.5, and 0.7.
Fisher, D. M., Holka, D., Telesman, J.
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Effect of yield stress on fatigue crack growth

open access: yesFracture and Structural Integrity, 2019
. Fatigue crack growth (FCG) depends on loading, geometry and also material properties. Since FCG is supposedly linked to crack tip plastic deformation, material’s yield stress, Y0, is an important parameter.
Fernando Ventura Antunes   +4 more
doaj   +3 more sources

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