Results 71 to 80 of about 3,307 (180)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of yield stress on fatigue crack growth

Fracture and Structural Integrity, 2019
. Fatigue crack growth (FCG) depends on loading, geometry and also material properties. Since FCG is supposedly linked to crack tip plastic deformation, material’s yield stress, Y0, is an important parameter.
Fernando Ventura Antunes, Micael Frias Borges, Pedro Prates, Ricardo Branco, Marta Oliveira   +4 more
doaj   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Mixed-mode thermo elastic delamination fracture behavior of composite skin stiffener containing interface delamination

Journal of Materials Research and Technology, 2019
This paper presents the thermo-elastic effect on materials having anisotropic behavior and stresses developed due to residual temperature on interlaminar delamination fracture characteristics of composite skin stiffener.
Saumya Shah, Pardeep Kumar, S.K. Panda, Sandeep Kumar   +3 more
doaj   +1 more source

Characterization of Microstructural Effects on Fatigue Crack Closure

, 1991
The growth of a fatigue crack is modified by the development of contacts between the crack faces1,2 creating shielding and thus canceling a portion of the applied load. These contacts develop through a number of mechanisms, including plastic deformation, sliding of the faces with respect to each other and the creation and collection of debris such as ...
Rehbein, David, Barnard, Dan, Buck, Otto
openaire   +3 more sources

Innovative reinforcement techniques for 3D-printed concrete: The impact of shape memory alloys on flexural strength and crack mitigation

Next Materials
The flexural performance (FP) of 3D Printed Concrete (3DPC) remains a challenge due to its limitations in tensile strength and resistance to cracking. To address these issues, innovative reinforcement materials, such as Shape Memory Alloys (SMAs), which ...
Ronak Motiani, Saha Keunang Sylvain, Sejal P. Dalal, Jay Vora, Rakesh Chaudhari   +4 more
doaj   +1 more source

Influence of roughness on the mechanical response of rock-like specimens with nonpersistent joints under uniaxial compression based on joint deformation analysis

Underground Space
Joint deformation is a key factor controlling the mechanical behavior of discontinuous rock strata under changing stress conditions, including dominating the elastic deformation in near-surface excavations and serving as a major component of settlement ...
Hong Yin, Zehui Gao, Yulong Shao, Shuhong Wang, Jae-Joon Song, Ye Wang, Jineon Kim, Shan Guo   +7 more
doaj   +1 more source

Modeling of creep-fatigue interaction effects on crack growth at elevated temperatures

MATEC Web of Conferences, 2018
The well-known load frequency effect on creep-fatigue crack growth is explained by the interactions between fatigue and creep loading and is quantified using the concept of plasticity-induced crack closure.
Potirniche Gabriel P.
doaj   +1 more source

Damage characteristics and energy storage evolution law of coal with pressure relief borehole

Meitan kexue jishu
In the environment of deep strong mining-induced stress, phenomena such as borehole collapse, closure and compaction are prone to occur in large-diameter pressure relief boreholes in coal seams, and the pressure relief effect shows obvious time-effect ...
Yanchun YIN, Tongbin ZHAO, Aiwen WANG, Chuanru YAO, Fangrui LIU, Xuepeng GAO   +5 more
doaj   +1 more source

Anisotropic FCGR behaviour in hot-rolled Mg-3Al-0.5Ce alloy

Journal of Magnesium and Alloys
In this work, anisotropic fatigue crack growth rate (FCGR) behaviour in a hot-rolled Mg-3wt%Al-0.5wt%Ce alloy was investigated using compact tension (CT) specimens with notch (an) parallel to the rolling direction (RD) and transverse direction (TD).
Prakash C. Gautam, Somjeet Biswas
doaj   +1 more source