Results 61 to 70 of about 1,354,072 (296)

Comparison between cohesive zone and coupled criterion modeling of crack initiation in rhombus hole specimens under quasi-static compression

open access: yesTheoretical and applied fracture mechanics (Print), 2019
Numerical predictions of initiation loading and crack length in a rhombus hole specimen made of a brittle material under quasi-static compression using either cohesive zone model or coupled criterion based on finite fracture mechanics are compared.
A. Doitrand, R. Estevez, D. Leguillon
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Study on Internal Fatigue Crack Initiation and Propagation Direction of Wind Turbine Gearbox Bearings

open access: yesJixie chuandong, 2022
The fatigue crack initiation direction of wind turbine gearbox bearings is investigated. Through theoretical research,it is believed that the direction of crack initiation depends on the direction of the maximum shear stress amplitude plane at the local ...
Haibo Sun, Feng Shen
doaj  

Evaluation of transverse crack initiation in interlaminar toughened CFRP cross-ply laminates under cyclic loading

open access: yesNihon Kikai Gakkai ronbunshu, 2014
Initiation and growth behaviors of a transverse crack occurred in interlaminar toughened CFRP cross-ply laminates under cyclic loading were evaluated. Specimens whose stacking sequence is [0/904]S and [0/906]S were formed with T800S/3900-2B prepreg.
Hiroyuki KAWADA   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Crack path in aeronautical titanium alloy under ultrasonic torsion loading

open access: yesFracture and Structural Integrity, 2015
This paper discusses features of fatigue crack initiation and growth in aeronautical VT3-1 titanium alloy under pure torsion loading in gigacycle regime. Two materials: extruded and forged VT3-1 titanium alloys were studied.
A. Nikitin   +3 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Research on the influence of high speed labyrinth rubbing on the initiation and propagation of crack in sealing ring

open access: yesHangkong gongcheng jinzhan
The rubbing of the labyrinth sealing structure is a common problem during the operation of aeroengine air system. Due to the difficulty in observing the process of crack initiation and propagation on the sealing ring during actual rubbing,using finite ...
CHANG Jiaqi   +5 more
doaj   +1 more source

Research on crack initiation mechanism and fracture criterion of rock-type materials under compression–shear stress

open access: yesAdvances in Mechanical Engineering, 2017
With the focus on the failure of single-cracked rocks under compression–shear stress, the form and the critical conditions of crack initiation by adopting theoretical derivation and numerical experiments methods are researched in this article.
Ling Yue   +4 more
doaj   +1 more source

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