Results 61 to 70 of about 28,118 (298)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2013 Shielding interaction effects of two parallel edge cracks in finite thickness plates subjected to remote tension load is analyzed using a developed finite element analysis program.
Mohd Aizat bin Mohamad Nor
core
, 2013 Link to publisher's homepage at http://www.ttp.net/Stress shielding interaction effect of two parallel edge cracks in finite body under uniaxial loading is analysed using developed finite element (FE) analysis program.
Mohd Shukry, Abdul Majid, Dr. +4 more
core +1 more source
Closure Effect of I + II Mixed-mode Crack for EA4T Axle Steel
Chinese Journal of Mechanical EngineeringThe crack-closure effect is a crucial factor that affects the crack growth rate and should be considered in simulation analysis and testing. A mixed-mode I + II loading fatigue crack growth test was performed using EA4T axle steel specimens.
Shuancheng Wang +4 more
doaj +1 more source
INTERACTION OF A INCLUSION WITH A CRACK
Acta Physica Sinica, 1990 The influence on the stress field in the vicinity of a crack tip due to a round inclusion is investigated. The antiplane shear problem is solved. After the classical stress field and stress strenth factor are obtained, the nonsingular nonlocal stresses in the vicinity of crack tip is obtained. The application of the solution is discussed.
openaire +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Fluid-crack Interaction In Hydraulic Fracturing
, 2015 Hydraulic fracturing has been one of the major improvements in petroleum engineering in the past few decades. Since then this process has been used progressively and over million wells have been fracked using hydraulic fracturing technology.
Vora, Harshil
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source