Results 81 to 90 of about 222,942 (303)
Influence of fatigue crack wake length and state of stress on crack closure [PDF]
The location of crack closure with respect to crack wake and specimen thickness under different loading conditions was determined. The rate of increase of K sub CL in the crack wake was found to be significantly higher for plasticity induced closure in ...
Fisher, D. M., Telesman, J.
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Line Spring Model and Its Applications to Part-Through Crack Problems in Plates and Shells [PDF]
The line spring model is described and extended to cover the problem of interaction of multiple internal and surface cracks in plates and shells. The shape functions for various related crack geometries obtained from the plane strain solution and the ...
Aksel, B., Erdogan, F.
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Interaction between a crack and a soft inclusion [PDF]
With the application to weld defects in mind, the interaction problem between a planar-crack and a flat inclusion in an elastic solid is considered.
Erdogan, F., Xue-Hui, L.
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Fracturing rock with ultra high pressure water [PDF]
, 2004 Modelling issues are considered for the process of cracking rock in mines using ultra high pressure water. The elevated pressures are caused by the ignition of a propellant and may be as large as 1000MPa.
Cheng, J. +5 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
AIP Advances, 2015 In this paper, the flux-pinning-induced elastic stress analysis considering the crack-inclusion interaction is carried out for a bulk superconductor in the magnetization process.
Feng Xue, Xiaofan Gou
doaj +1 more source
Relation of cyclic loading pattern to microstructural fracture in creep fatigue [PDF]
Creep-fatigue-environment interaction is discussed using the 'strainrange partitioning' (SRP) framework as a basis. The four generic SRP strainrange types are studied with a view of revealing differences in micromechanisms of deformation and fatigue ...
Halford, G. R. +2 more
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