Results 71 to 80 of about 28,118 (298)

Two end variable singularity boundary elements and their applications in crack-crack interaction problems

, 2000
Two new boundary elements have been proposed for simulation of variable order singularities at the two ends of an element in two dimensions. The first can model the variable order strain singularity at both the ends of the element. The second element can
Mukhopadhyay, N. K., Kakodkar, Anil, Maiti, S. K.   +2 more
core   +1 more source

Insights into the X-shaped fissure propagation and interaction mechanisms of rock specimens: 3D printing experiments and DEM simulations

Case Studies in Construction Materials
X-shaped fissures are prevalent in natural rocks and significantly influence rock mass stability, yet their interaction and propagation mechanisms remain inadequately studied.
Yiqing Sun, Wei Huang, Lei Gan, Zhenzhong Shen, Hongwei Zhang, Wenbing Zhang   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Faking it: a conceptual discussion on emotional labor, emotional dissonance and emotional intelligence

, 2018
Emotional labor is a construct that is intertwined with the hospitality industry as employees are required to accommodate certain behavior or emotion to conform with the idea of providing excellent and sincere service to guests or customers.
Ibrahim, Mohd Zool Fadli, Salim, Azlan, Rohiat, Mohd Akmal, Raja Mustapha, Raja Iskandar Putera, Mohamad Saber, Joesri   +4 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Seismic water-crack interaction in gravity dams : experimental study and numerical simulations [PDF]

, 2003
Water pressure in cracks and and joints of concrete Dams : state-of-the-art -- Seismic analysis of gravity dams -- Uplift pressure -- Water flow in cracks -- Transient seismic uplift in concrete cracks of gravity dams -- Compressibility of water ...
Javanmardi, Farrokh
core  

Evaluation of chloride penetration resistance of concrete with superabsorbent polymers under the interaction of fatigue load and temperature

Case Studies in Construction Materials
Long-term chloride ion penetration is a critical concern for the durability of pavement concrete subjected to the interaction of fatigue load and temperature variation. This study explores the effects of superabsorbent polymers (SAP) and such interaction
Aiqin Shen, Yixuan Wang, Guiping Ren, Yinchuan Guo, Hongxu Cui   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Stiffness Reduction in Laminates at High Intralaminar Crack Density: Effect of Crack Interaction

, 2011
The previously developed closed form expressions for thermo-elastic properties of laminates with intralaminar cracks (Lundmark and Varna, 2005) contain crack surface opening and sliding as main local parameters.
Varna, Janis,, Lundmark, Peter,
core   +1 more source