Results 91 to 100 of about 2,476,755 (297)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The purpose of this article is to present the stress intensity factors (SIF) solutions for semi-elliptic crack in pipelines under internal pressures, the stress intensity factors are calculated by the three-dimensional finite element method (FEM) for ...
Djamel Eddine Belhadri +3 more
doaj
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Predicting fatigue crack growth rate in a welded butt joint: The role of effective R ratio in accounting for residual stress effect [PDF]
A simple and efficient method is presented in this paper for predicting fatigue crack growth rate in welded butt joints. Three well-known empirical crack growth laws are employed using the material constants that were obtained from the base material ...
Servetti, Guido, Zhang, X.
core +1 more source
Experimental Study on Mixed Mode Crack Propagation
Abstract The cracked specimens which are made of four kinds of brittle material have been tested under all possible combinations of modes I, II and III. On the basis of measured data, an empirical criterion of mixed mode crack propagation 0.05(K 1 /K Ic ) 2 + 0.95(K 1 /K Ic ) + 2.16(K 2 /K Ic ) 2 +
openaire +2 more sources
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
A new impact test for the identification of a dynamic crack propagation criterion using a gas-gun device [PDF]
The modelling of damage and fracture behaviour under high rates of loadings for metallic structures presents the more and more interests for engineering design, especially for crash phenomena.In order to perform a numerical simulation of such phenomena a
I. Nistor +5 more
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Experimental and numerical study on mixed mode I/II fatigue crack growth in planar specimens
S.823-830This paper focuses on the evaluation of predictive methods for the analysis of fatigue crack growth (FCG) under mixed mode I/II loading. The experimental part of the study consists of a series of fatigue crack growth tests performed on bend and ...
Kadau, K. +4 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source

