Results 81 to 90 of about 2,476,755 (297)

Numerical study of crack path by MMCG specimen using M integral [PDF]

open access: yesFracture and Structural Integrity, 2016
The mixed mode loading configuration occurs in many civil engineering and mechanical applications. In wood material, the study of this problem is very important due to the orthotropic character and the heterogeneity of the material.
S. El Kabir   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Evaluating Pavement Cracks with Bidimensional Empirical Mode Decomposition [PDF]

open access: yesEURASIP Journal on Advances in Signal Processing, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nii Attoh-Okine, Albert Ayenu-Prah
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Characterization of crack nucleation in TA6V under fretting-fatigue loading using the potential drop technique [PDF]

open access: yes, 2010
Crack initiation in a Ti-6Al-4V alloy was investigated experimentally in fretting fatigue conditions. A cylinder-plane geometry was used for the contact, and partial slip conditions were considered.
Deyber, S.   +11 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Fatigue crack growth behaviour and life prediction for 2324-T39 and 7050-T7451 aluminium alloys under truncated load spectra [PDF]

open access: yes, 2010
This paper presents a study of crack growth behaviour in aluminium alloys 2324- T39 and 7050-T7451 subjected to flight-by-flight load spectra at different low- stress truncation levels. Crack branching was observed in the higher truncation levels for the
Bao, Rui, Zhang, Xiang
core   +1 more source

The study of influence law about mode II crack propagation

open access: yes工程科学与技术, 2016
:In order to study the impact of the normal compression on shear (mode II) crack propagation, Sandstone is used to make the unilateral crack specimen. Shear experiment on cracks which are under different normal compression loads was carried out by rock ...
Helian, Zhu Zheming
doaj  

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