Results 61 to 70 of about 30,437 (264)
Crack Damage Identification of Pantograph Upper Frame Elbow Joint Based on Strain Mode
ObjectiveThe structural safety of pantograph has a significant impact on the operational reliability of trains. Fatigue cracks are prone to occur at the elbow joints of pantograph on high-speed trains.
Haixiang GAO +6 more
doaj +1 more source
Growth mechanism of a fatigue crack of extruded high strength Al alloy 7075-T6 in high humidity
Effect of humidity on the growth mechanism of a fatigue crack in an age-hardened Al alloy was investigated in relative humidity environments of 25% and 85% at loading frequencies of 50Hz and 6Hz.
Norio KAWAGOISHI +5 more
doaj +1 more source
Crack propagation in fracture mechanical graded structures [PDF]
The focus of manufacturing is more and more on innovative and application-oriented products considering lightweight construction. Hence, especially functional graded materials come to the fore.
B. Schramm, H.A. Richard
doaj +1 more source
A mode-III crack with variable surface effects
We study the contribution of variable surface effects to the antiplane deformation of a linearly elastic material with a mode-III crack. The surface elasticity is incorporated using a modified version of the continuum based surface/interface model of Gurtin and Murdoch.
Wang, Xu, Schiavone, Peter
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
MIXED-MODE CRACK GROWTH IN WOOD
In timber elements the mixed mode depends essentially of wood anatomy and load configuration.In these conditions, in order to evaluate the material behavior and the fracture process, it’s necessary to separate the part of each mode. The mixed mode separation allows evaluating the amplitude of fracture mode. In the present paper, using a mixedmode crack
Pop, Octavian +2 more
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source

