Results 61 to 70 of about 4,438,483 (347)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Growth mechanism of a fatigue crack of extruded high strength Al alloy 7075-T6 in high humidity
Nihon Kikai Gakkai ronbunshu, 2015 Effect of humidity on the growth mechanism of a fatigue crack in an age-hardened Al alloy was investigated in relative humidity environments of 25% and 85% at loading frequencies of 50Hz and 6Hz.
Norio KAWAGOISHI +5 more
doaj +1 more source
Vietnam Journal of Mechanics, 2020 The problem of using the modal curvature for crack detection is discussed in this paper based on an exact expression of mode shape and its curvature.
Nguyen Tien Khiem
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Crack Damage Identification of Pantograph Upper Frame Elbow Joint Based on Strain Mode
Chengshi guidao jiaotong yanjiuObjectiveThe structural safety of pantograph has a significant impact on the operational reliability of trains. Fatigue cracks are prone to occur at the elbow joints of pantograph on high-speed trains.
Haixiang GAO +6 more
doaj +1 more source
FRACTURE CRITERIA FOR COMBINED MODE CRACKS
, 1978 The complex variable method is employed to analyse the energy release rate for combined mode cracks. A functional integral equation, which contains no singularity, is derived for a branched crack problem by a functional transformation. The integrand φ_1'(z) is expanded in eigenfunctions. The energy fracture criterion for the combined mode (K_Ⅰ and K_Ⅱ)
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
C1− Continuous crack propagation for mixed-mode fracture problems [PDF]
, 2013 In this work a C1− continuous crack propagation algorithm is proposed to improve the numerical simulation of localized deformation patterns, using higher order elements.
Hendriks, M.A.N. +2 more
core
The influence of material anisotropy and spiral welding on tensile strain capacity of spiral welded pipes [PDF]
, 2015 The longitudinal strain capacity of spiral welded pipelines displays to some extents unexplained behaviour. Therefore, they are not (yet) used extensively in offshore applications and harsh conditions, demanding a strain based design. An important factor
De Backer, Michiel +2 more
core +2 more sources
MIXED-MODE CRACK GROWTH IN WOOD
Pro Ligno, 2012 In timber elements the mixed mode depends essentially of wood anatomy and load configuration.In these conditions, in order to evaluate the material behavior and the fracture process, it’s necessary to separate the part of each mode. The mixed mode separation allows evaluating the amplitude of fracture mode. In the present paper, using a mixedmode crack
Pop, Octavian +2 more
openaire +2 more sources