Results 61 to 70 of about 403,344 (296)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Surface Crack Shape Evolution Modelling using an RMS SIF approach [PDF]
, 2010 The majority of fatigue cracks in thick plate and tubular sections in structural components are two-dimensional surface cracks having significant propagation lives before becoming critical.
Han, S. K. +2 more
core +1 more source
An Adaptive Crack Width Prediction for Flexural Steel Reinforced UHPC Beams
International Journal of Concrete Structures and Materials, 2023 The crack pattern of steel reinforced ultrahigh performance concrete (UHPC) beam is usually characterized by many densely distributed fine cracks (i.e., multiple microcracks) along with localized macrocrack, and the crack width development rate along the
Yanping Zhu +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Meitan kexue jishuIn response to the natural cleavage in the coal rock body, there are multiple crack initiation and expansion of the engineering perturbation of the mutual influence of the problem, produced 30 prefabricated cleavage width of 0.3 mm, respectively ...
Hongyun FAN +4 more
doaj +1 more source
Effect of Holes on Dynamic Crack Propagation under Impact Loading
Applied Sciences, 2020 In civil, geotechnical, and mining engineering, the investigation of the holes’ effect on dynamic crack propagation is essential because it can be used to predict possible fracture and protect cracked structures being further damaged. In this paper,
Fei Wang, Meng Wang
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
, 2008 An assessment of the effects of microstructure on room temperature fatigue crack initiation and short crack propagation in a Ni-base superalloy is presented.
Pang, H.T., Reed, P.A.S.
core +1 more source
Influence of corrosion and creep on intergranular fatigue crack path in 2XXX aluminium alloys [PDF]
, 2010 In this paper, two examples of the influence of time-dependent processes on crack path in two 2XXX aluminium alloys are presented. The first example is concerned with corrosion–fatigue crack growth resistance of a 2024 T351 alloy cracked in the S–L ...
Odemer, Grégory +2 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source