Results 81 to 90 of about 403,344 (296)

Characteristics of crack expansion and borehole co-deformation of coal containing double boreholes during failure

open access: yesMeitan kexue jishu
The cooperative arrangement of gas extraction boreholes and pressure relief boreholes can effectively control compound disasters of coal and gas outburst-rock burst in deep mines.
Xiang JI   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Fatigue crack shielding in plain bearings under large scale yielding

open access: yes, 2010
Multi-layered bearing systems used in the automotive industry show shielding and antishielding effects that reduce or amplify the crack driving force under large-scale yielding conditions. Using finite element analysis, it is shown that shielding in such
S. Syngellakis   +5 more
core   +1 more source

Influence of Charge Hole Spacing on the Crack Propagation Behavior under the Effect of Empty-Hole Directional Blasting

open access: yesAdvances in Civil Engineering, 2020
In order to explore the reasonable spacing of charge holes in empty-hole directional blasting, based on the action mechanism of empty-hole directional blasting, the influence of charge hole spacing on crack propagation is studied, the calculation formula
Guobin Tian   +4 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Nonlinear dynamics of a rotating shaft with a breathing crack [PDF]

open access: yes, 2011
In this paper, the effects of a breathing crack on the vibratory characteris- tics of a rotating shaft are investigated. A new, simple and robust model composed of two rigid bars connected with a nonlinear flexural spring is proposed.
Saber El Arem   +3 more
core   +1 more source

A comprehensive study on estimating the primary crack spacing of flexural reinforced concrete components using machine learning techniques

open access: yesAdvanced Modeling and Simulation in Engineering Sciences
Accurate estimation of primary crack spacing in flexural reinforced concrete components is essential for serviceability assessment and durability-related decision making. This study evaluates eleven regression-based machine learning models, combined with
Ahed Habib   +5 more
doaj   +1 more source

Reinforcement Strains in Reinforced Concrete Tensile Members Recorded by Strain Gauges and FBG Sensors: Experimental and Numerical Analysis

open access: yesSensors, 2019
Experimental and numerical studies have been carried out on reinforced concrete (RC) short tensile specimens. Double pull-out tests employed rectangular RC elements of a length determined not to yield any additional primary cracks. Tests were carried out
Gintaris Kaklauskas   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Flexural behaviour of ferrocement. [PDF]

open access: yes, 1982
Ferrocement is often believed to be a form of reinforced concrete. However, in spite of the similarities between the two materials there are still major differences, indicating that ferrocement requires a separate study to establish its structural ...
Alwash, Abdul Salam A
core   +3 more sources

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