Results 21 to 30 of about 68,059 (240)

Q&A: Morphological insights into evolution

open access: yesBMC Biology, 2017
In this question and answer article we discuss how evolution shapes morphology (the shape and pattern of our bodies) but also how learning about morphology, and specifically how that morphology arises during development, can shed light on mechanisms that
Neal Anthwal, Abigail S. Tucker
doaj   +1 more source

egfl6 expression in the pharyngeal pouch is dispensable for craniofacial development

open access: yesAnimal Cells and Systems, 2021
Epidermal growth factor-like domain multiple 6 (Egfl6) is a basement membrane protein and plays an important role in hair follicle morphogenesis, angiogenesis, notochord development in vertebrates.
Sil Jin   +4 more
doaj   +1 more source

Postnatal Craniofacial Skeletal Development of Female C57BL/6NCrl Mice

open access: yesFrontiers in Physiology, 2017
The craniofacial skeleton is a complex and unique structure. The perturbation of its development can lead to craniofacial dysmorphology and associated morbidities.
Xiaoxi Wei   +5 more
doaj   +1 more source

Single-Cell Transcriptome Analysis Defines Expression of Kabuki Syndrome-Associated KMT2D Targets and Interacting Partners

open access: yesStem Cells International, 2022
Objectives. Kabuki syndrome (KS) is a rare genetic disorder characterized by developmental delay, retarded growth, and cardiac, gastrointestinal, neurocognitive, renal, craniofacial, dental, and skeletal defects.
Badam Enkhmandakh   +6 more
doaj   +1 more source

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. [PDF]

open access: yesPLoS Genetics, 2015
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously
John N Griffin   +4 more
doaj   +1 more source

A Reciprocal Interaction between β-Catenin and Osterix in Cementogenesis

open access: yesScientific Reports, 2017
Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis.
Hwajung Choi   +5 more
doaj   +1 more source

Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis

open access: yesNature Communications, 2016
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse ...
Yaopan Mao   +7 more
doaj   +1 more source

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

open access: yesBMC Genomics, 2018
Background Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate.
Maria Zoupa   +5 more
doaj   +1 more source

Candidate genes for obstructive sleep apnea in non-syndromic children with craniofacial dysmorphisms – a narrative review

open access: yesFrontiers in Pediatrics, 2023
Pediatric obstructive sleep apnea (POSA) is a complex disease with multifactorial etiopathogenesis. The presence of craniofacial dysmorphisms influencing the patency of the upper airway is considered a risk factor for POSA development.
Zuzana Marincak Vrankova   +12 more
doaj   +1 more source

High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development

open access: yesCell Reports, 2018
Summary: Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within ...
Andrea Wilderman   +4 more
doaj   +1 more source

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