Results 21 to 30 of about 68,059 (240)
Q&A: Morphological insights into evolution
In this question and answer article we discuss how evolution shapes morphology (the shape and pattern of our bodies) but also how learning about morphology, and specifically how that morphology arises during development, can shed light on mechanisms that
Neal Anthwal, Abigail S. Tucker
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egfl6 expression in the pharyngeal pouch is dispensable for craniofacial development
Epidermal growth factor-like domain multiple 6 (Egfl6) is a basement membrane protein and plays an important role in hair follicle morphogenesis, angiogenesis, notochord development in vertebrates.
Sil Jin +4 more
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Postnatal Craniofacial Skeletal Development of Female C57BL/6NCrl Mice
The craniofacial skeleton is a complex and unique structure. The perturbation of its development can lead to craniofacial dysmorphology and associated morbidities.
Xiaoxi Wei +5 more
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Objectives. Kabuki syndrome (KS) is a rare genetic disorder characterized by developmental delay, retarded growth, and cardiac, gastrointestinal, neurocognitive, renal, craniofacial, dental, and skeletal defects.
Badam Enkhmandakh +6 more
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The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. [PDF]
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously
John N Griffin +4 more
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A Reciprocal Interaction between β-Catenin and Osterix in Cementogenesis
Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis.
Hwajung Choi +5 more
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Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse ...
Yaopan Mao +7 more
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Gene expression profiling in the developing secondary palate in the absence of Tbx1 function
Background Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate.
Maria Zoupa +5 more
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Pediatric obstructive sleep apnea (POSA) is a complex disease with multifactorial etiopathogenesis. The presence of craniofacial dysmorphisms influencing the patency of the upper airway is considered a risk factor for POSA development.
Zuzana Marincak Vrankova +12 more
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High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development
Summary: Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within ...
Andrea Wilderman +4 more
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