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Creatine in Health and Disease [PDF]

Nutrients, 2021
Although creatine has been mostly studied as an ergogenic aid for exercise, training, and sport, several health and potential therapeutic benefits have been reported.
R. Kreider, J. Stout
semanticscholar   +4 more sources

Hemispheric asymmetry in high-energy phosphate consumption during sleep-deprivation is balanced by creatine [PDF]

Frontiers in Neuroscience
The human brain exhibits asymmetric hemispheric activity at night; this plays a crucial role in cognitive impairment from sleep deprivation. Although there have been many investigations on this topic, there are no studies on hemispheric differences in ...
Ali Gordji-Nejad, Andreas Matusch, Sophie Kleedörfer, Harshal Jayeshkumar Patel, Alexander Drzezga, Alexander Drzezga, Alexander Drzezga, David Elmenhorst, David Elmenhorst, Ferdinand Binkofski, Ferdinand Binkofski, Andreas Bauer   +11 more
doaj   +2 more sources

Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart [PDF]

, 2014
Background: Multiple studies suggest creatine mediates anti-oxidant activity in addition to its established role in cellular energy metabolism.
Aksentijević, Dunja, Faller, Kiterie M.E., Lygate, Craig A., McAndrew, Debra J., Neubauer, Stefan, Schneider, Jurgen E., Zazueta, Cecilia, Zervou, Sevasti   +7 more
core   +7 more sources

Transcriptional Regulation of the Creatine Utilization Genes of Corynebacterium glutamicum ATCC 14067 by AmtR, a Central Nitrogen Regulator

Frontiers in Bioengineering and Biotechnology, 2022
In the genus Corynebacterium, AmtR is a key component of the nitrogen regulatory system, and it belongs to the TetR family of transcription regulators.
Hao Zhang, Hao Zhang, Zhilin Ouyang, Zhilin Ouyang, Nannan Zhao, Nannan Zhao, Shuangyan Han, Shuangyan Han, Suiping Zheng, Suiping Zheng   +9 more
doaj   +1 more source

Effects of Creatine Supplementation on Brain Function and Health

Nutrients, 2022
While the vast majority of research involving creatine supplementation has focused on skeletal muscle, there is a small body of accumulating research that has focused on creatine and the brain.
Scott C. Forbes, Dean M. Cordingley, S. Cornish, B. Gualano, H. Roschel, S. Ostojić, E. Rawson, B. Roy, K. Prokopidis, P. Giannos, D. Candow   +10 more
semanticscholar   +1 more source

Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review

Nutrients, 2022
In 2011, we published a paper providing an overview about the bioavailability, efficacy, and regulatory status of creatine monohydrate (CrM), as well as other “novel forms” of creatine that were being marketed at the time.
R. Kreider, R. Jäger, M. Purpura
semanticscholar   +1 more source

Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?

Journal of the International Society of Sports Nutrition, 2021
Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in ...
J. Antonio, D. Candow, Scott C. Forbes, B. Gualano, Andrew R. Jagim, R. Kreider, E. Rawson, A. Smith‐Ryan, Trisha A. VanDusseldorp, D. Willoughby, T. Ziegenfuss   +10 more
semanticscholar   +1 more source

Creatine Supplementation and Brain Health

Nutrients, 2021
There is a robust and compelling body of evidence supporting the ergogenic and therapeutic role of creatine supplementation in muscle. Beyond these well-described effects and mechanisms, there is literature to suggest that creatine may also be beneficial
H. Roschel, B. Gualano, Sergej M Ostojic, Eric S Rawson   +3 more
semanticscholar   +1 more source

Serum Creatine, Not Neurofilament Light, Is Elevated in CHCHD10-Linked Spinal Muscular Atrophy

Frontiers in Neurology, 2022
ObjectiveTo characterize serum biomarkers in mitochondrial CHCHD10-linked spinal muscular atrophy Jokela (SMAJ) type for disease monitoring and for the understanding of pathogenic mechanisms.MethodsWe collected serum samples from a cohort of 49 patients ...
Julius Järvilehto, Sandra Harjuhaahto, Edouard Palu, Mari Auranen, Jouni Kvist, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Johanna Koskivuori, Marko Lehtonen, Anna Maija Saukkonen, Manu Jokela, Manu Jokela, Emil Ylikallio, Emil Ylikallio, Henna Tyynismaa, Henna Tyynismaa, Henna Tyynismaa   +18 more
doaj   +1 more source

Creatine for Exercise and Sports Performance, with Recovery Considerations for Healthy Populations

Nutrients, 2021
Creatine is one of the most studied and popular ergogenic aids for athletes and recreational weightlifters seeking to improve sport and exercise performance, augment exercise training adaptations, and mitigate recovery time.
B. Wax, C. Kerksick, Andrew R. Jagim, J. Mayo, B. Lyons, R. Kreider   +5 more
semanticscholar   +1 more source