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Creatine Kinase and Blood Pressure: A Systematic Review

open access: yesMedical Sciences, 2019
Background: Hypertension is a main risk factor for premature death. Although blood pressure is a complex trait, we have shown that the activity of the ATP-generating enzyme creatine kinase (CK) is a significant predictor of blood pressure and of failure ...
L. M. Brewster   +2 more
doaj   +1 more source

Creatine supplementation and its influence on human organism

open access: yesJournal of Education, Health and Sport, 2022
Background: Creatine supplementation is one of the most popular methods of improving athletic performance. In this article we reviewed its positive and negative influence on human organism.
Wojciech Siedlecki   +9 more
doaj   +1 more source

Effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players [PDF]

open access: yes, 2001
The purpose of this study was to determine the effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players. Nine squash players (mean ± SEM V˙O2max = 61.9 ± 2.1ml · kg-1 · min-1; body mass =
Barrington, JP   +2 more
core   +1 more source

International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

open access: yesJournal of the International Society of Sports Nutrition, 2017
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have consistently shown that creatine supplementation increases intramuscular creatine concentrations which may help explain the observed improvements in high intensity ...
R. Kreider   +9 more
semanticscholar   +1 more source

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

open access: yesFrontiers in Physiology, 2022
Creatine serves as an ATP buffer and is thus an integral component of cellular energy metabolism. Most cells maintain their creatine levels via uptake by the creatine transporter (CRT-1, SLC6A8).
Clemens V. Farr   +5 more
doaj   +1 more source

The Potential Role of Creatine in Vascular Health

open access: yesNutrients, 2021
Creatine is an organic compound, consumed exogenously in the diet and synthesized endogenously via an intricate inter-organ process. Functioning in conjunction with creatine kinase, creatine has long been known for its pivotal role in cellular energy ...
H. Clarke, R. Hickner, M. Ormsbee
semanticscholar   +1 more source

Muscle Damage following Maximal Eccentric Knee Extensions in Males and Females [PDF]

open access: yes, 2016
Aim: To investigate whether there is a sex difference in exercise induced muscle damage. Materials and Method: Vastus Lateralis and patella tendon properties were measured in males and females using ultrasonography.
Hicks, Kirsty   +3 more
core   +1 more source

Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice

open access: yesFrontiers in Pharmacology, 2018
Statins are the preferred therapy to treat hypercholesterolemia. Their main action consists of inhibiting the cholesterol biosynthesis pathway. Previous studies report mitochondrial oxidative stress and membrane permeability transition (MPT) of several ...
Ana C. Marques   +5 more
doaj   +1 more source

The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer [PDF]

open access: yes, 2018
Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis.
Fairman, C M   +5 more
core   +2 more sources

Creatine and creatine analogues in hypertension and cardiovascular disease [PDF]

open access: yesCochrane Database of Systematic Reviews, 2011
The creatine kinase system, the central regulatory system of cellular energy metabolism, provides ATP in situ at ATP-ases involved in ion transport and muscle contraction. Furthermore, the enzyme system provides relative protection from tissue ischaemia and acidosis.
Inge Oudman   +3 more
openaire   +3 more sources

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