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Creatine Kinase and Blood Pressure: A Systematic Review
Background: Hypertension is a main risk factor for premature death. Although blood pressure is a complex trait, we have shown that the activity of the ATP-generating enzyme creatine kinase (CK) is a significant predictor of blood pressure and of failure ...
L. M. Brewster+2 more
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Creatine supplementation and its influence on human organism
Background: Creatine supplementation is one of the most popular methods of improving athletic performance. In this article we reviewed its positive and negative influence on human organism.
Wojciech Siedlecki+9 more
doaj +1 more source
Effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players [PDF]
The purpose of this study was to determine the effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players. Nine squash players (mean ± SEM V˙O2max = 61.9 ± 2.1ml · kg-1 · min-1; body mass =
Barrington, JP+2 more
core +1 more source
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have consistently shown that creatine supplementation increases intramuscular creatine concentrations which may help explain the observed improvements in high intensity ...
R. Kreider+9 more
semanticscholar +1 more source
Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1
Creatine serves as an ATP buffer and is thus an integral component of cellular energy metabolism. Most cells maintain their creatine levels via uptake by the creatine transporter (CRT-1, SLC6A8).
Clemens V. Farr+5 more
doaj +1 more source
The Potential Role of Creatine in Vascular Health
Creatine is an organic compound, consumed exogenously in the diet and synthesized endogenously via an intricate inter-organ process. Functioning in conjunction with creatine kinase, creatine has long been known for its pivotal role in cellular energy ...
H. Clarke, R. Hickner, M. Ormsbee
semanticscholar +1 more source
Muscle Damage following Maximal Eccentric Knee Extensions in Males and Females [PDF]
Aim: To investigate whether there is a sex difference in exercise induced muscle damage. Materials and Method: Vastus Lateralis and patella tendon properties were measured in males and females using ultrasonography.
Hicks, Kirsty+3 more
core +1 more source
Statins are the preferred therapy to treat hypercholesterolemia. Their main action consists of inhibiting the cholesterol biosynthesis pathway. Previous studies report mitochondrial oxidative stress and membrane permeability transition (MPT) of several ...
Ana C. Marques+5 more
doaj +1 more source
The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer [PDF]
Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis.
Fairman, C M+5 more
core +2 more sources
Creatine and creatine analogues in hypertension and cardiovascular disease [PDF]
The creatine kinase system, the central regulatory system of cellular energy metabolism, provides ATP in situ at ATP-ases involved in ion transport and muscle contraction. Furthermore, the enzyme system provides relative protection from tissue ischaemia and acidosis.
Inge Oudman+3 more
openaire +3 more sources