Is creatine a CNS neurotransmitter?
eLife, 2023 A range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system.
Bhagaban Mallik, C Andrew Frank
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Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. [PDF]
, 2019 The 26S proteasome is essential for proteostasis and the regulation of vital processes through ATP-dependent degradation of ubiquitinated substrates. To accomplish the multi-step degradation process, the proteasomes regulatory particle, consisting of lid
Aufderheide +42 more
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Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise [PDF]
, 2014 Peer ...
Chappell, Andrew John +4 more
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Creatine Supplementation in Children and Adolescents
Nutrients, 2021 Creatine is a popular ergogenic aid among athletic populations with consistent evidence indicating that creatine supplementation also continues to be commonly used among adolescent populations.
Andrew R. Jagim, C. Kerksick
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Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]
, 2010 Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey +3 more
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Supplementation of creatine and its role in brain function
Journal of Education, Health and Sport, 2023 Introduction and aim. In recent years growing awareness of the society regarding healthy lifestyle leads to increased interest in regular physical activity and usage of dietary supplements.
Leila Abod +4 more
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International Society of Sports Nutrition position stand: beta-alanine [PDF]
, 2015 Position statement: The International Society of Sports Nutrition (ISSN) provides an objective and critical review of the mechanisms and use of beta-alanine supplementation.
Antonio, J +13 more
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The Potential Role of Creatine in Vascular Health
Nutrients, 2021 Creatine is an organic compound, consumed exogenously in the diet and synthesized endogenously via an intricate inter-organ process. Functioning in conjunction with creatine kinase, creatine has long been known for its pivotal role in cellular energy ...
H. Clarke, R. Hickner, M. Ormsbee
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Magnetic Resonance Spectroscopy in Diagnosing Brain Tumours? Is it Worth Doing [PDF]
International Journal of Anatomy Radiology and Surgery, 2019 Introduction: Magnetic Resonance Spectroscopy (MRS) is a non-invasive diagnostic method useful in providing information about specific metabolites in brain tissue that can indicate the presence of tumour, necrotic tissue and other pathologic entities.
Sunita Dashottar +1 more
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Guanidinoacetic Acid as a Nutritional Adjuvant to Multiple Sclerosis Therapy
Frontiers in Human Neuroscience, 2022 Tackling impaired bioenergetics in multiple sclerosis (MS) has been recently recognized as an innovative approach with therapeutic potential. Guanidinoacetic acid (GAA) is an experimental nutrient that plays a significant role in high-energy phosphate ...
Sergej M. Ostojic +2 more
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