Results 181 to 190 of about 73,335 (261)

Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders

Neuroprotection, Volume 4, Issue 1, Page 30-47, March 2026.
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan, Roshan S. Raghavan, Dawn Li Wei Koh, Wing Yeng Tan, Igor Iezhitsa, Renu Agarwal   +5 more
wiley   +1 more source

Paeonia lactiflora Callus-Derived Polynucleotides Enhance Collagen Accumulation in Human Dermal Fibroblasts. [PDF]

J Funct Biomater
Hwang S, Park S, Lee JW, Park M, Nguyet LA, Hwang Y, Ahn K, Shin HY, Son KH.   +8 more
europepmc   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Cytoplasmic Translocation of the Transcription Factor pCREB and Altered Proteostasis in Human Islet Cells During Type 1 Diabetes Development. [PDF]

J Histochem Cytochem
Teitelman G.
europepmc   +1 more source

Relationship Between Gut Microbiota and Cancer Neuro‐Immunity

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
Tumour cells influence neural activity and microbiota homeostasis through cytokines and immune modulation. Meanwhile, gut microbiota regulates neural function through metabolic products, affects immune responses via neurotransmitters, feedback regulates neural activity and influences tumour microenvironment.
Danyang Wang, Ruirui Cui, Chang You, Wanlin Zheng, Luyao Wang, Yingqi Yang, Hongkai Yu, Bota Cui   +7 more
wiley   +1 more source

Molecular Characterization of the Murine Catsper4 Promoter and its Regulation by CREMτ. [PDF]

Reprod Sci
López-Guzmán SF, Sánchez-Jasso DE, Hernández-Sánchez J, Oviedo N, Bermudez-Cruz RM.   +4 more
europepmc   +1 more source

Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice

Aging Cell, Volume 25, Issue 3, March 2026.
The left panel shows cerebral lactate homeostasis in young mice. The middle panel displays accelerated ANLS rates due to FGF21 secretion in aging mice. The right panel demonstrates that lactate uptake and usage inhibition contribute to lactate extracellular accumulation, followed by HCA1‐mediated learning and memory decline in mice.
Keru Ji, Hongde Wei, Ruguang Wang, Yutong Wu, Chen Li, Hongchang Gao, Liangcai Zhao   +6 more
wiley   +1 more source

GLP-1RA in JBMMSCs promoted osteogenic differentiation via modulating CREB and BRD4 signaling mediated proliferation and stemness. [PDF]

Sci Rep
Liu H, Tian Y, Bao X, Li Y.
europepmc   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, Volume 36, Issue 2, March 2026.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

Senescent Fibroblasts Drive Melanoma Progression Through GCP-2 Induced CREB Phosphorylation Enhancing Glycolysis. [PDF]

Aging Cell
Basu A, Farsam V, Singh K, Crisan D, Treiber N, Schneider LA, Huber M, Engelmeyer JI, Schumacher B, Maity P, Brandt D, Jastroch M, Mauch C, Geiger H, Kletsas D, Scharffetter-Kochanek K.   +15 more
europepmc   +1 more source