Nature and Science of Sleep, 2021 Hui Shen, Yanling Meng, Dan Liu, Zheng Qin, Hong Huang, Lei Pan, Wei Wang, Jian Kang Institute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Wei WangInstitute of ...
Shen H +7 more
doaj
Studying the Effect of Lactobacillus fermentum on Arc and CREB Genes Expression of Involved in The Memory of Alzheimer\'s Rats [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023 Introduction: Alzheimer's disease is a common progressive neurogenerative disease that leads to dementia and destruction of brain cells, especially in areas related to learning and memory such as the hippocampus.
Elnaz Mogaddam +3 more
doaj
β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H [PDF]
, 2016 CREB-H is an endoplasmic reticulum-resident bZIP transcription factor which critically regulates lipid homeostasis and gluconeogenesis in the liver. CREB-H is proteolytically activated by regulated intramembrane proteolysis to generate a C-terminally ...
Chan, CP +6 more
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Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
Cells, 2019 Increased vascular smooth muscle cell (VSMC) proliferation contributes towards restenosis after angioplasty, vein graft intimal thickening and atherogenesis.
Sarah A. Smith +2 more
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Contribution of CaMKIV to injury and fear- induced ultrasonic vocalizations in adult mice [PDF]
, 2005 Calcium-calmodulin dependent protein kinase IV (CaMKIV) is a protein kinase that activates the transcription factor CREB. Our previous work demonstrated that mice lacking CaMKIV had a defect in fear memory while behavioral responses to noxious stimuli ...
Chatila, Talal +2 more
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DHA (omega-3 fatty acid) increases the action of brain-derived neurotrophic factor (BDNF)
Oilseeds and fats, crops and lipidsNeurons have high energy needs, requiring a continuous supply of glucose from the blood. Tight regulation of glucose metabolism in response to stimuli is essential for brain physiology.
Majou Didier, Dermenghem Anne-Lise
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PABPN1 functions as a downstream gene of CREB to inhibit the proliferation of preadipocytes [PDF]
Animal BioscienceObjective This study was conducted to reveal the role of nuclear poly(A) binding protein 1 (PABPN1) in the proliferation of preadipocytes, and to reveal the relationship between PABPN1 and cAMP response element (CRE)-binding protein (CREB) in the ...
Xiao-Han Zhang +7 more
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Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice. [PDF]
CNS Neurosci TherJia‐zhan Huang et al. describe a function of prefrontal TRPM8 in the regulation of epileptic seizures. TRPM8 receptors was upregulated in the prefrontal cortex (PFC) of epileptic mice. Inhibition or knockdown of TRPM8 in PFC can effectively prolong the latency and reduce the level of seizures in mouse models induced by pentatetrazole. At the same time,
Huang JZ +6 more
europepmc +2 more sources
Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]
, 2015 Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean +5 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source