Results 91 to 100 of about 23,863,179 (302)

The creep model based on nonlinear Newton body under different temperature conditions. [PDF]

Sci Rep, 2023
Zhang L, Wei X, Zhang Y.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Creep constitutive model considering nonlinear creep degradation of fractured rock

International Journal of Mining Science and Technology
Stability analysis of underground constructions requires a model study of rock masses’ long-term performance. Creep tests under different stress conditions was conducted on intact granite and granite samples fractured at 30° and 45° angles. The experimental results indicate that the steady creep strain rates of intact and fractured rock present an ...
Wang Chunping, Liu Jianfeng, Chen Liang, Liu Jian, Wang Lu, Liao Yilin   +5 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Research on the Creep Model of Deep Coal Roadway and Its Numerical Simulation Reproduction. [PDF]

Int J Environ Res Public Health, 2022
Zhang Q, Wang E, Ding Z.
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Study on shear creep model of calcareous sand in China South Sea

Frontiers in Earth Science
The creep characteristics of calcareous sand have an important impact on the stability of the structures on the coral islands in the South China Sea. Among the existing creep models for calcareous sand, fewer models consider the particle fragmentation of
Bin Tang, Bin Tang, Xingyun Huang, Weitao Zhong   +3 more
doaj   +1 more source

Influence of Temperature, Humidity and Load Coupling on Mechanical Properties of Adhesive Joints and Establishment of Creep Model. [PDF]

Polymers (Basel), 2023
Tan W, Zhou Z, Na J, Mu W.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Fuzzy random evaluation of creep model of frozen soft soil in metro tunnel construction using artificial ground freezing technique. [PDF]

Sci Rep, 2023
Yao Y, Zhu Y, Shen D, Zhang Z, Wang W.
europepmc   +1 more source