Results 91 to 100 of about 29,880 (311)

Understanding the creep behaviors and mechanisms of Mg-Gd-Zn alloys via machine learning

Journal of Magnesium and Alloys
Mg-Gd-Zn based alloys have better creep resistance than other Mg alloys and attract more attention at elevated temperatures. However, the multiple alloying elements and various heat treatment conditions, combined with complex microstructural evolution ...
Shuxia Ouyang, Xiaobing Hu, Qingfeng Wu, Jeong Ah Lee, Jae Heung Lee, Chenjin Zhang, Chunhui Wang, Hyoung Seop Kim, Guangyu Yang, Wanqi Jie   +9 more
doaj   +1 more source

Extended Residual-State Creep Test and Its Application for Landslide Stability Assessment. [PDF]

Materials (Basel), 2021
Bhat DR, Kozubal JV, Tankiewicz M.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Determining Full Stage Creep Properties from Miniature Specimen Creep Test

, 2018
In this work, methods for determining creep properties which can be used to represent the full life until failure from miniature specimen creep tests based on analytical solutions are presented. Examples used to demonstrate the application of the methods
A. A. Becker, W. Wen, J. Lu, W. Sun
core   +1 more source

Time-scale effect of the creep model parameters and particle flow simulation of sandstone with a single crack

Yantu gongcheng xuebao, 2019
The creep deformation behaviors of the hard rocks in deep high-stress environment, especially for the fractured hard rocks, cannot be neglected. To investigate the long-term creep deformation behaviors and the creep model for the fractured hard rock, the
HU Bo 1, YANG Sheng-qi 1,2, XU Peng 3, TIAN Wen-ling 1
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Compressive Creep Test on Fiber-Reinforced Ultra-High Performance Concrete: Effects of Strain Measuring Method, Specimen Size, Sustained Load Intensity, and Fiber Length

Buildings
To solve the difficulties in applying the compressive creep test method for normal concrete to UHPC and to verify the validity of the recently proposed ASTM C 1856 standard test method, this study performed compressive creep tests on UHPC with the ...
Hyun-Myo Park, Seung-Ryong Ryu, Oh Kyun Kwon, Jun-Mo Yang   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Creep: time‐dependent brittle deformation in rocks

, 2009
The characterization of time‐dependent brittle rock deformation is fundamental to understanding the long‐term evolution and dynamics of the Earth’s crust. The chemical influence of pore water promotes time‐dependent deformation through stress corrosion
Heap, M.J.
core