Results 101 to 110 of about 75,389 (334)

Cultural-historical mounuments of town of Cres

, 2020
Prisutnost brojnih dvoraca, palača bogatih renesansnih obitelji, značajnih renesansnih crkvica, kao i gradskih loža i vrata, daju Cresu bogati kulturno – povijesni značaj za hrvatsku kulturnu baštinu.
Vukelić, Aleksandra
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PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Benin profile on tobacco taxation : adopt a more effective taxation and better inform tobacco products prevalence [PDF]

, 2018
The 2015 Survey of Risk Factors for Chronic Diseases in Benin (STEPS) indicates that smoking is declining significantly from 16% of adult smokers, in 2007 to 5% in 2015.
Consortium for Economic and Social Research (CRES)
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Anti-Ureaplasma urealyticum activities of CRES.

, 2013
(A) Ureaplasma urealyticum (Uu) incubated with 100 ng/ml GST, GST-CRES and buffer for 0 h, 18 h and 36 h. (B) Uu incubated with 100 ng/ml GST (purple), GST-CRES (orange) and buffer (green) for 0 h, 12 h, 18 h, 24 h and 36 h.
Qing Yuan (297461), Meige Lu (297464), Chen Xu (53797), Heng Cai (122597), Yue Liu (292931), Sunhong Chen (297463), Li Wang (15202)   +6 more
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Cre-ating Ways to Serotonin [PDF]

Frontiers in Neuroscience, 2010
Almost 50 years ago Dahlstrom and Fuxe discovered serotonergic neurons in the brainstem. Much remains to learn, however, about how serotonin (5-hydroxytryptamine or 5HT) modulates circuit activity. Serotonergic neurons release 5HT throughout the CNS. Accordingly, these cells influence breathing rhythms, body temperature, heart rate, pain, eating, sleep,
openaire   +3 more sources

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Epigenomics and transcriptomics profiles of developing zebrafish heart cells

Scientific Data
cis-Regulatory elements (cREs) are essential for the spatio-temporal control of gene expression during development and disease. However, cRE activity is highly dependent on cell and tissue type.
Gulrez Chahal, Michael P. Eichenlaub, Markus Tondl, Michał Pawlak, Monika Mohenska, Lin Grimm, Lauren Bottrell, Mark Drvodelic, Sara Alaei, Jeannette Hallab, Lisa N. Waylen, Jose M. Polo, Cédric Blanpain, Nathan Palpant, Fernando J. Rossello, Minna-Liisa Änkö, Peter D. Currie, Benjamin M. Hogan, Cecilia Winata, Ekaterina Salimova, Hieu T. Nim, Mirana Ramialison   +21 more
doaj   +1 more source

Efectes de la Covid-19 a les llistes d’espera de la Catalunya Central: quin coll d’ampolla té més influència per a la disminució entre 2019 i 2020 dels diagnòstics de càncer?

, 2021
TFG (UPF), dirigit per Guillem López i Casasnovas, Catedràtic d’Economia de la Universitat Pompeu Fabra, Centre de Recerca en Economia i Salut ...
Sabater Mezquita, Roger
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