Results 71 to 80 of about 75,389 (334)

On the design of a solar heat storage tank at 120°C

International Journal of Sustainable Energy, 2023
This work presents the materials selection process, the design and the dimensioning process of a latent heat storage tank that works between a high temperature heat pump and an Organic Rankine Cycle unit.
R. Christodoulaki, I. S. Akmandor, O. Bayer, U. Desideri, L. Ferrari, G. F. Frate, V. Drosou   +6 more
doaj   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Use of a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting post-extubation adverse respiratory events among elderly patients in an anesthesia intensive care unit

BMC Pulmonary Medicine, 2023
Objective The purpose of this study was to examine the feasibility of using a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting adverse respiratory events after extubation among elderly patients in an anesthetic ...
Lun Huang, Bo Xia, Lei Cheng, Xian-Wen Hu, Li-Dong Zheng, Feng Cheng   +5 more
doaj   +1 more source

Hydroeographical characteristics of Vrana lake on Cres island

, 2022
Vransko jezero na Cresu golema je kriptodepresija u kojoj se nalazi 220 milijuna m3 pitke vode koja opskrbljuje stanovništvo otoka Cresa, Lošinja i Ilovika. Jezero se nalazi u središnjem dijelu otoka Cresa a njime upravlja komunalno društvo Vodoopskrba i
Damijanjević, Luka
core  

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

An Amphibious Fully‐Soft Centimeter‐Scale Miniature Crawling Robot Powered by Electrohydraulic Fluid Kinetic Energy

Advanced Science
Miniature locomotion robots with the ability to navigate confined environments show great promise for a wide range of tasks, including search and rescue operations.
Quan Xiong, Xuanyi Zhou, Dannuo Li, Jonathan William Ambrose, Raye Chen‐Hua Yeow   +4 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Cis-Active RNA Elements (CREs) and Picornavirus RNA Replication

Virus Research, 2008
Our understanding of picornavirus RNA replication has improved over the past 10 years, due in large part to the discovery of cis-active RNA elements (CREs) within picornavirus RNA genomes.
B. Steil, D. Barton
semanticscholar   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.

Journal of Biological Chemistry, 1994
Chorionic gonadotropin (CG) is a heterodimeric placental hormone encoded by separate alpha and beta subunit genes that is essential for the maintenance of pregnancy. The production of CG is stimulated by DNA synthesis inhibitors and by cAMP.
R. Pestell, A. Hollenberg, C. Albanese, J. Jameson   +3 more
semanticscholar   +1 more source