Results 51 to 60 of about 52,471 (263)

Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor

Frontiers in Endocrinology, 2018
The corticotropin-releasing factor (CRF) system is a key mediator of the stress response and addictive behavior. The CRF system includes four peptides: The CRF system includes four peptides: CRF, urocortins I–III, CRF binding protein (CRF-BP) that binds ...
Paula G. Slater, Sebastian E. Gutierrez-Maldonado, Katia Gysling, Carlos F. Lagos   +3 more
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Être Malade Chronique : Exercer un Métier au Service du Maintien de Soi en Vie et Transformer son Expérience en Expertise

Sisyphus, 2018
Resumé La modification des trajectoires thérapeutiques dans les maladies chroniques a modifié les parcours de soin des personnes vivant avec une maladie chronique.
Catherine Tourette-Turgis, Lennize Pereira-Paulo   +1 more
doaj   +1 more source

Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed
Kristine Røren Nordén, Anne Grete Semb, Hanne Dagfinrud, Jonny Hisdal, Sigrid Ødegård, Joseph Sexton, Camilla Fongen, Jon Skandsen, Thalita Blanck, George S. Metsios, Anne Therese Tveter   +10 more
doaj   +1 more source

ICSI-CRF [PDF]

Proceedings of the 2009 Workshop on Language Generation and Summarisation - UCNLG+Sum '09, 2009
In this paper, we describe our contribution to the Generation Challenge 2009 for the tasks of generating Referring Expressions to the Main Subject References (MSR) and Named Entities Generation (NEG). To generate the referring expressions, we employ the Conditional Random Fields (CRF) learning technique due to the fact that the selection of an ...
Benoit Favre, Bernd Bohnet
openaire   +1 more source

Metal Ion‐Induced Fast Gelation of 2D MnO2 Nanosheets With Cationic Vacancies for Durable Aqueous Zinc‐Ion Batteries

Advanced Science, EarlyView.
We report Mn‐deficient aerogels by inducing the first gelation of MnO2 nanosheets in solution using divalent metal ions as crosslinking agents, thereby inhibiting nanosheet restacking and enhancing surface utilization. Benefiting from abundant Mn vacancies and 3D porous structures, the A‐MnO2 cathode exhibits improved conductivity, fast reaction ...
Yalei Wang, Xinyu Huang, Shulong Chang, Bowen Li, Caichao Ye, Feng Yang, Yahui Xue   +6 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Generation of Nasal Cell‐Derived Human Alveolar Organoids and Organoid‐Macrophage Assembloids for in Vitro Lung Modeling

Advanced Science, EarlyView.
This study demonstrates the generation of human alveolar organoids from nasal cells, which, when co‐cultured with monocyte‐derived macrophages, promotes maturation of both components and forms alveolar assembloids resembling native alveoli. These alveolar organoids and assembloids offer accessible, physiologically relevant in vitro systems for ...
Man Chun Chiu, Shuxin Zhang, Cun Li, Yifei Yu, Zhixin Wan, Jingjing Huang, Wei Xue, Ying Zhou, Xiaoxin Zhu, Qiaoshuai Lan, Jiali Wu, Zijun Zhao, Yuhong Liu, Xinjie Meng, Lin Huang, Hin Chu, Honglin Chen, Kelvin Kai‐Wang To, Kwok Yung Yuen, Jie Zhou   +19 more
wiley   +1 more source

Chinese Grammatical Error Diagnosis Based on CRF and LSTM-CRF model [PDF]

Proceedings of the 5th Workshop on Natural Language Processing Techniques for Educational Applications, 2018
When learning Chinese as a foreign language, the learners may have some grammatical errors due to negative migration of their native languages. However, few grammar checking applications have been developed to support the learners. The goal of this paper is to develop a tool to automatically diagnose four types of grammatical errors which are redundant
Yujie Zhou, Yinan Shao, Yong Zhou
openaire   +1 more source

Integrated Bipolar Membrane Electrodialysis and Electrolysis for CO2 Capture and Conversion

Advanced Energy Materials, EarlyView.
This work demonstrates an integrated BMEED platform that couples CO2 capture and conversion within a single modular system. By combining BMED with CO2E, high‐purity CO is produced while avoiding intermediate stripping, excessive capital and O&M costs, and external gas feeds.
Hyuck Joo Choi, Hakhyeon Song, Mohammed Tahmid, Hyeonuk Choi, Jihun Oh, Marta C. Hatzell   +5 more
wiley   +1 more source