Results 71 to 80 of about 52,471 (263)

Caving‐enhanced geothermal system overwhelms fracturing‐ and pipe‐enhanced geothermal system in heat extraction

Deep Underground Science and Engineering, EarlyView.
Our study reveals that caving‐enhanced geothermal systems (C‐EGS) with adequately fractured reservoirs achieve optimal heat extraction by minimizing preferential flow paths, while conventional fracturing (F‐EGS) and pipe‐based (P‐EGS) systems suffer accelerated thermal drawdown.
Fangchao Kang, Tianjiao Li, Yingchun Li, Jinlong Men, Chun'an Tang   +4 more
wiley   +1 more source

Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior

Frontiers in Neuroscience, 2013
Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis.
James H Fox, Christopher A Lowry
doaj   +1 more source

One‐Year Results of Accelerated Transepithelial Corneal Cross‐Linking for Progressive Keratoconus: A Prospective Interventional Study

Eye &ENT Research, EarlyView.
ABSTRACT Background Keratoconus is a progressive corneal ectatic disorder. Accelerated transepithelial corneal cross‐linking (ATE‐CXL) aims to halt progression while preserving the epithelium, but evidence on its 12‐month efficacy requires further evaluation.
Rafea Allawi Fayyadh, Omar Salim Mahmood, Aktham Badia Abdulelah, Husam Abu Dawood, Hashem Abu Serhan   +4 more
wiley   +1 more source

Short‐Term Changes in Cardiorespiratory Fitness in Response to Exercise Training and the Association with Long‐Term Cardiorespiratory Fitness Decline: The STRRIDE Reunion Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Substantial heterogeneity exists in the cardiorespiratory fitness (CRF) change in response to exercise training, and its long‐term prognostic implication is not well understood.
Ambarish Pandey, Johanna L. Johnson, Cris A. Slentz, Leanna M. Ross, Vijay Agusala, Jarett D. Berry, William E. Kraus   +6 more
doaj   +1 more source

Fully automated three‐dimensional deep learning‐based magnetic resonance imaging segmentation of brain cavities in epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective There are several clinical and research applications for determining the amount of brain tissue resected after epilepsy surgery; however, manual segmentation of postoperative magnetic resonance imaging (MRI) is imprecise and time‐consuming.
Raphael Fernandes Casseb, Brunno Machado de Campos, Wallace Souza Loos, Marcelo Eduardo Ramos Barbosa, Marina Koutsodontis Machado Alvim, Gabriel Chagas Lutfala Paulino, Enrico Ghizoni, Francesco Pucci, Samuel Worrell, Clarissa Lin Yassuda, Roberto Medeiros de Souza, Lara Jehi, Fernando Cendes   +12 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior.

PLoS ONE, 2009
Stress is a complex human experience and having both rewarding and aversive motivational properties. The adverse effects of stress are well documented, yet many of underlying mechanisms remain unclear and controversial. Here we report that the anxiogenic
Michael R Bruchas, Benjamin B Land, Julia C Lemos, Charles Chavkin   +3 more
doaj   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi, Jonathan Ipser, James T. Butler, Heath Pardoe, Hamid Soltanian‐Zadeh, Christian Rummel, Roland Wiest, Simon S. Keller, Barbara A. K. Kreilkamp, Anna Elisabetta Vaudano, Alice Ballerini, Stefano Meletti, Gerard Hall, Peter Taylor, Luis Concha, Alfonso Fajardo‐Valdez, Raphael Fernandes Casseb, Fernando Cendes, Clarissa L. Yasuda, Louis Lemieux, John S. Duncan, Esmaeil Davoodi‐Bodj, Orrin Devinsky, Sophia I. Thomopoulos, Dan J. Stein, Paul M. Thompson, Sanjay M. Sisodiya, Taha Gholipour, Carrie R. McDonald   +28 more
wiley   +1 more source

CRF binding protein activity in the hypothalamic paraventricular nucleus is essential for stress adaptations and normal maternal behaviour in lactating rats

Neurobiology of Stress
To ensure the unrestricted expression of maternal behaviour peripartum, activity of the corticotropin-releasing factor (CRF) system needs to be minimised.
Alice Sanson, Paula Krieg, Milena M. Schramm, Kerstin Kellner, Rodrigue Maloumby, Stefanie M. Klampfl, Paula J. Brunton, Oliver J. Bosch   +7 more
doaj   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, EarlyView.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source