Results 81 to 90 of about 164,927 (267)

Analysis of HIV-1 genetic variants and drug resistance among men with high-risk sexual behavior, Cuban citizens, living in Moscow in 2022–2024

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Introduction. The characteristics of the HIV epidemic in Cuba are comparable to those of the HIV epidemic in Russia. Migration between Cuba and Russia can affect HIV-1 genetic diversity and drug resistance in Russia. The vulnerable group of men with risk
Ilya A. Lapovok   +5 more
doaj   +1 more source

Design and Optimization of a Novel Kalina‐Organic Rankine Cycle System Based on LNG Cold Energy Utilization

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a novel integrated system (SDKC‐DORC) that combines a split‐flow dual‐pressure Kalina cycle with a secondary organic Rankine cycle for the synergistic utilization of solar energy and liquefied natural gas (LNG) cold energy.
Ke Xiao   +6 more
wiley   +1 more source

Developing medication independence: The experience of UK teenagers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins   +5 more
wiley   +1 more source

Generalized CRF-structures [PDF]

open access: yesGeometriae Dedicata, 2008
A generalized F-structure is a complex, isotropic subbundle $E$ of $T_cM\oplus T^*_cM$ ($T_cM=TM\otimes_{\mathds{R}}\mathds{C}$ and the metric is defined by pairing) such that $E\cap\bar E^{\perp}=0$. If $E$ is also closed by the Courant bracket, $E$ is a generalized CRF-structure.
openaire   +3 more sources

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

Être Malade Chronique : Exercer un Métier au Service du Maintien de Soi en Vie et Transformer son Expérience en Expertise

open access: yesSisyphus, 2018
Resumé La modification des trajectoires thérapeutiques dans les maladies chroniques a modifié les parcours de soin des personnes vivant avec une maladie chronique.
Catherine Tourette-Turgis   +1 more
doaj   +1 more source

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz   +15 more
wiley   +1 more source

Corticotrophin-Releasing Factor Modulates Cerebellar Purkinje Cells Simple Spike Activity in Vivo in Mice

open access: yesFrontiers in Cellular Neuroscience, 2018
Corticotropin-releasing factor (CRF) is a major neuromodulator that modulates cerebellar neuronal activity via CRF receptors during stress responses. In the cerebellar cortex, CRF dose-dependently increases the simple spike (SS) firing rate of Purkinje ...
Hong-Wei Wang   +15 more
doaj   +1 more source

Clinical Perspectives on Incorporating Cardiorespiratory Fitness in Clinical Practice

open access: yes, 2018
Cardiorespiratory fitness (CRF) has been documented as a strong, independent predictor of non-communicable disease and mortality in both clinical and apparently healthy populations. This well-established relationship has impelled organizations, including
Fleenor, Bradley S.   +5 more
core  

Caving‐enhanced geothermal system overwhelms fracturing‐ and pipe‐enhanced geothermal system in heat extraction

open access: yesDeep Underground Science and Engineering, EarlyView.
Our study reveals that caving‐enhanced geothermal systems (C‐EGS) with adequately fractured reservoirs achieve optimal heat extraction by minimizing preferential flow paths, while conventional fracturing (F‐EGS) and pipe‐based (P‐EGS) systems suffer accelerated thermal drawdown.
Fangchao Kang   +4 more
wiley   +1 more source

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