Results 101 to 110 of about 164,927 (267)

The Clinical Efficacy of High‐Voltage Long‐Duration Pulsed Radiofrequency Treatment in Pudendal Neuralgia: A Retrospective Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley   +1 more source

CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior.

open access: yesPLoS ONE, 2009
Stress is a complex human experience and having both rewarding and aversive motivational properties. The adverse effects of stress are well documented, yet many of underlying mechanisms remain unclear and controversial. Here we report that the anxiogenic
Michael R Bruchas   +3 more
doaj   +1 more source

Diagnostic Performance of Comprehensive Point‐of‐Care Ultrasound for Pediatric Tuberculosis in Spain: A Prospective Observational Study

open access: yesJournal of Clinical Ultrasound, EarlyView.
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju   +17 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

G-DEFINER CRFs

open access: yes, 2020
https://gdefiner.net/ Project: "Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment" (G-DEFINER). Clinical study CRFs. (DOI of the Study Protocol: 10.5281/zenodo.4142124) This is a multicenter observational prospective clinical study aimed at investigating the inequalities between female (F) and male (M ...
openaire   +1 more source

REVEAL AD ‐ Prevalence of Moderate and Severe Atopic Dermatitis in Ireland: A Cross‐ Sectional, Real World Study of a Secondary Care Population

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a common inflammatory skin disease. However, limited data exist on its prevalence and incidence in Irish secondary care. Objectives REVEAL AD had two distinct but related objectives: (1) Estimate prevalence of moderate‐to‐severe AD in patients aged 12 years and older presenting to secondary care clinics in ...
Oisín S. Gough   +6 more
wiley   +1 more source

The CRF domain defines Cytokinin Response Factor proteins in plants

open access: yesBMC Plant Biology, 2010
Background Cytokinin Response Factors (CRFs) are a small subset of AP2/ERF transcription factor genes shown in Arabidopsis to regulate leaf development as part of the cytokinin signal transduction pathway.
Goertzen Leslie R, Rashotte Aaron M
doaj   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

CRF binding protein activity in the hypothalamic paraventricular nucleus is essential for stress adaptations and normal maternal behaviour in lactating rats

open access: yesNeurobiology of Stress
To ensure the unrestricted expression of maternal behaviour peripartum, activity of the corticotropin-releasing factor (CRF) system needs to be minimised.
Alice Sanson   +7 more
doaj   +1 more source

From Offline to Inline Without Pain: A Practical Framework for Translating Offline MR Reconstructions to Inline Deployment Using the Gadgetron Platform

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and validate a practical, open‐source framework to overcome common issues in inline deployment of established offline MR reconstruction, including (1) scan disruption from lengthy reconstructions, (2) limited support for multi‐scan input reconstructions, (3) needs to adapt scripts for different raw‐data formats, and (4 ...
Zihan Ning   +26 more
wiley   +1 more source

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