Results 61 to 70 of about 29,752 (188)

MiRNA-34 and stress response [PDF]

, 2017
Psychiatric disorders are known to result from a strong interaction between genetic predisposition and environmental factors, mainly exposure to stressful events. Environmental events can modulate genes expression, possibly via epigenetic mechanisms, and
Andolina, Diego, DI SEGNI, Matteo, Ventura, Rossella   +2 more
core   +1 more source

Altered maternal profiles in corticotropin-releasing factor receptor 1 deficient mice

BMC Neuroscience, 2007
Background During lactation, the CNS is less responsive to the anxiogenic neuropeptide, corticotropin-releasing factor (CRF). Further, central injections of CRF inhibit maternal aggression and some maternal behaviors, suggesting decreased CRF ...
Bethea Emily D, Gammie Stephen C, Stevenson Sharon A   +2 more
doaj   +1 more source

Teneurins, TCAP, and latrophilins: roles in the etiology of mood disorders

Translational Neuroscience, 2016
Mood disorders, including anxiety and depression, are thought to be characterized by disrupted neuronal synapses and altered brain plasticity. The etiology is complex, involving numerous regions of the brain, comprising a multitude of neurotransmitter ...
Woelfle Rebecca, D’Aquila Andrea L., Lovejoy David A.   +2 more
doaj   +1 more source

Effects of olmesartan on arterial stiffness in rats with chronic renal failure

Cardiovascular Diabetology, 2012
Background It has been suggested that the antioxidant properties of olmesartan (OLM), an angiotensin II type 1 receptor (AT1R) blocker, contribute to renal protection rather than blood pressure lowering effects despite the fact that causal relationships ...
Chuang Yao-Chen, Wu Ming-Shiou, Su Yi-Kai, Fang Kwang-Ming   +3 more
doaj   +1 more source

Plasma Corticotropin-Releasing Factor Receptors and B7-2⁺ Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity. [PDF]

, 2019
Extracellular vesicles (EVs) are composed of bilayer membranes that are released by different cell types and are present in bodily fluids, such as blood, urine, and bile. EVs are thought to play a key role in intracellular communication.
Bhargava, Aditi, Chang, Lin, Hagiwara, Shin-Ichiro, Hasdemir, Burcu, Heyman, Melvin B   +4 more
core   +1 more source

Contrasting effects of nitric oxide and corticotropin- releasing factor within the dorsal periaqueductal gray on defensive behavior and nociception in mice

Brazilian Journal of Medical and Biological Research, 2012
The anxiogenic and antinociceptive effects produced by glutamate N-methyl-D-aspartate receptor activation within the dorsal periaqueductal gray (dPAG) matter have been related to nitric oxide (NO) production, since injection of NO synthase (NOS ...
T.T. Miguel, K.S. Gomes, R.L. Nunes-de-Souza   +2 more
doaj   +2 more sources

Susceptibility to obesity and gallbladder stasis produced by a protein- and fat-enriched diet in male mice compared with female mice

Nutrition & Metabolism, 2007
Background The frequency of Japanese subjects over 20 years old with metabolic syndrome is 45.6% in men but just 16.7% in women. The reason why Japanese male subjects are more susceptible to metabolic syndrome than women is unknown.
Takiguchi Soichi, Akimoto Saeko, Sekime Ayako, Ohta Minoru, Kanai Setsuko, Miyasaka Kyoko, Funakoshi Akihiro   +6 more
doaj   +1 more source

LATEST ADVANCES FOR TREATING CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY

İstanbul Tıp Fakültesi Dergisi
Congenital adrenal hyperplasia (CAH) is a group of inherit ed diseases characterised by disrupted glucocorticoid (GC) and mineralocorticoid (MC) synthesis in the adrenal glands.
Ecesu Çetin, Mehmet Furkan Burak
doaj   +1 more source

CB1 Receptor Antagonism Blocks Stress-Potentiated Reinstatement of Cocaine Seeking in Rats [PDF]

, 2015
Rationale Under some conditions, stress, rather than directly triggering cocaine seeking, potentiates reinstatement to other stimuli, including a subthreshold cocaine dose.
Baker, David A., Doncheck, Elizabeth M., Ganzman, Geoffrey S., Hillard, Cecilia J., Mantsch, John R., McReynolds, Jayme R., Vranjkovic, Oliver   +6 more
core   +2 more sources

Urocortin-1 within the centrally-projecting Edinger-Westphal nucleus is critical for ethanol preference.

PLoS ONE, 2011
Converging lines of evidence point to the involvement of neurons of the centrally projecting Edinger-Westphal nucleus (EWcp) containing the neuropeptide Urocortin-1 (Ucn1) in excessive ethanol (EtOH) intake and EtOH sensitivity.
William J Giardino, Davelle L Cocking, Simranjit Kaur, Christopher L Cunningham, Andrey E Ryabinin   +4 more
doaj   +1 more source