Viral Diversity Threshold for Adaptive Immunity in Prokaryotes [PDF]
mBio, 2012 Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas ...
Ariel D. Weinberger +4 more
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Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium. [PDF]
PLoS ONE, 2015 CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Alexandra E Briner +9 more
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Functional Coupling and Evolutionary Relationships Between Toxin–Antitoxin Systems and CRISPR-Cas Systems [PDF]
ToxinsBacteria encode a broad range of survival and defence systems, including CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas systems, restriction-modification systems, and toxin–antitoxin (TA) systems, which are involved in bacterial ...
Yibo Meng, Jiyun Chen, Liang Liu
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CRISPR-Cas systems in prokaryotes [PDF]
Polish Journal of Microbiology, 2015 Prokaryotic organisms possess numerous strategies that enable survival in hostile conditions. Among others, these conditions include the invasion of foreign nucleic acids such as bacteriophages and plasmids.
Burmistrz, Michał, Pyrć, Krzysztof
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Distribution of Genetic Determinants Associated with CRISPR-Cas Systems and Resistance to Antibiotics in the Genomes of Archaea and Bacteria [PDF]
MicroorganismsThe CRISPR-Cas system represents an adaptive immune mechanism found across diverse Archaea and Bacteria, allowing them to defend against invading genetic elements such as viruses and plasmids. Despite its broad distribution, the prevalence and complexity
Laura Antequera-Zambrano +4 more
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Mechanisms regulating the CRISPR-Cas systems
Frontiers in Microbiology, 2023 The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats- CRISPR associated proteins) is a prokaryotic system that enables sequence specific recognition and cleavage of nucleic acids.
Marta Zakrzewska +3 more
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Characterization of Ligilactobacillus salivarius CRISPR-Cas systems [PDF]
mSphereLigilactobacillus is a diverse genus among lactobacilli with phenotypes that reflect adaptation to various hosts. CRISPR-Cas systems are highly prevalent within lactobacilli, and Ligilactobacillus salivarius, the most abundant species of ...
Avery Roberts +4 more
doaj +2 more sources
Comprehensive Analysis of CRISPR-Cas Systems and Their Influence on Antibiotic Resistance in Strains [PDF]
Bioinformatics and Biology InsightsSalmonella enterica is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in S.
Tina Fallah, Morvarid Shafiei
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Genome mining approach reveals the CRISPR-Cas systems features and characteristics in Lactobacillus delbrueckii strains [PDF]
HeliyonThis study employed a comprehensive genome-mining approach to characterize CRISPR-Cas systems in Lactobacillus delbrueckii strains. The analysis involved retrieving 105 genome sequences to explore the variety, occurrence, and evolution of CRISPR-Cas ...
Bahman Panahi +3 more
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CASPredict: a web service for identifying Cas proteins [PDF]
PeerJ, 2021 Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated (Cas) proteins constitute the CRISPR-Cas systems, which play a key role in prokaryote adaptive immune system against invasive foreign elements.
Shanshan Yang, Jian Huang, Bifang He
doaj +2 more sources