Results 41 to 50 of about 58,663 (324)
Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems
Advanced Science, 2021 CRISPR‐Cas systems are a form of prokaryotic adaptive immunity that employs RNA‐guided endonucleases (Cas effectors) to cleave foreign genetic elements.
Vanja Perčulija +3 more
doaj +1 more source
Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]
, 2013 The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
White, Malcolm F., Zhang, Jing
core +2 more sources
Epidemiological and evolutionary consequences of different types of CRISPR-Cas systems.
PLoS Computational Biology, 2022 Bacteria have adaptive immunity against viruses (phages) in the form of CRISPR-Cas immune systems. Currently, 6 types of CRISPR-Cas systems are known and the molecular study of three of these has revealed important molecular differences. It is unknown if
Hélène Chabas +3 more
doaj +1 more source
New CRISPR-Cas systems discovered [PDF]
Cell Research, 2017 In bacteria and archaea, CRISPR-Cas adaptive immune systems utilize RNA-guided endonucleases to defend against invasion by foreign nucleic acids of bacteriophage, virus and plasmid origin. In a recent paper published in Nature, Burstein et al. identified the first Cas9 protein in uncultivated archaea and two novel CRISPR-CasX and CRISPR-CasY systems in
Dinshaw J. Patel, Hui Yang
openaire +3 more sources
Production and analysis of synthetic Cascade variants [PDF]
, 2020 CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR assoziiert) ist ein adaptives Immunsystem in Archaeen und Bakterien, das fremdes genetisches Material mit Hilfe von Ribonukleoprotein-Komplexen erkennt und zerstört.
Gleditzsch, Daniel
core +1 more source
Nanocarriers: A novel strategy for the delivery of CRISPR/Cas systems
Frontiers in Chemistry, 2022 In recent decades, clustered regularly interspaced short palindromic repeat/CRISPR-associated protein (CRISPR/Cas) has become one of the most promising genome-editing tools for therapeutic purposes in biomedical and medical applications.
Faranak Hejabi +5 more
doaj +1 more source
Strategies for High-Efficiency Mutation Using the CRISPR/Cas System
Frontiers in Cell and Developmental Biology, 2022 Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems have revolutionized traditional gene-editing tools and are a significant tool for ameliorating gene defects.
Shuying Feng +10 more
doaj +1 more source
Insights into the CRISPR/Cas system of Gardnerella vaginalis [PDF]
BMC Microbiology, 2012 Gardnerella vaginalis is identified as the predominant colonist of the vaginal tracts of women diagnosed with bacterial vaginosis (BV). G. vaginalis can be isolated from healthy women, and an asymptomatic BV state is also recognised. The association of G.
Plečkaitytė, Milda, +2 more
openaire +5 more sources
Efficient genome editing in zebrafish using a CRISPR-Cas system [PDF]
, 2013 In bacteria, foreign nucleic acids are silenced by clustered, regularly interspaced, short palindromic repeats (CRISPR)--CRISPR-associated (Cas) systems.
Fu, Yanfang +8 more
core +1 more source
Frontiers in Microbiology, 2018 Prokaryotic CRISPR-Cas systems limit the acquisition of genetic elements and provide immunity against invasive bacteriophage. The characteristics of CRISPR-Cas systems in clinical Klebsiella pneumoniae isolates are still unknown. Here, 97 K.
Hsin-Yu Li +8 more
doaj +1 more source