Results 11 to 20 of about 277,742 (368)
CRISPR-Cas Biochemistry and CRISPR-Based Molecular Diagnostics.
Angewandte Chemie International Edition, 2023 Polymerase chain reaction (PCR)-based nucleic acid testing has played a critical role in disease diagnostics, pathogen surveillance, and many more. However, this method requires a long turnaround time, expensive equipment, and trained personnel, limiting
Zhengyan Weng +7 more
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Genome Biology, 2015 The biological arms race generally involves the rapid co-evolution of anti-virus systems in host organisms and of anti-anti-virus systems in their viral parasites. The CRISPR-Cas system is an example of a prokaryotic immune system in which such co-evolution occurs, as was recently demonstrated by the characterization of a set of viral anti-CRISPR ...
van der Oost, John, Brouns, S.J.J.
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CRISPRing into the woods [PDF]
GM Crops & Food, 2015 The CRISPR/Cas9 technology is a welcome breakthrough for genome editing, owing to its precision, efficiency, versatility and ease of adoption. We recently reported the first application of CRISPR/Cas9 for biallelic mutations in stably transformed Populus, extending the species range of this powerful technology to woody perennials.
Liang-Jiao Xue, Chung-Jui Tsai
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Cell, 2016 Three years ago, scientists reported that CRISPR technology can enable precise and efficient genome editing in living eukaryotic cells. Since then, the method has taken the scientific community by storm, with thousands of labs using it for applications from biomedicine to agriculture.
Eric S. Lander +2 more
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Nature Biomedical Engineering, 2020 In less than a decade, the genome-editing technology now recognized by the Nobel Prize in Chemistry has impacted the biological and biomedical sciences widely. What’s next for CRISPR in biomedicine?
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CRISPR-Cas Systems for Detection of Nucleic Acids: PCR Empire now has a Vigorous Rival!
Translational Research in Urology, 2021 Rapid and accurate detection of nucleic acids is essential in many fields of modern biology and medical diagnosis of pathogens. PCR has some disadvantages for performing this task, and therefore demand for an alternative is highly appreciated.
Roham Deyhimfar
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CRISPR/Cas9 therapeutics: progress and prospects
Signal Transduction and Targeted Therapy, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting disease-
Tianxiang Li +9 more
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Off-target effects in CRISPR/Cas9 gene editing
Frontiers in Bioengineering and Biotechnology, 2023 Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence. With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient ...
Congting Guo +3 more
semanticscholar +1 more source
RNA Biology, 2013 CRISPR loci consist of an array of short repeats separated by spacer sequences that match the genome of viruses and plasmids that infect prokaryotes. Transcription of the CRISPR array generates small antisense RNAs that mediate immunity against these invaders.
Asma Hatoum-Aslan +2 more
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Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica
Magna Scientia UCEVA, 2021 El objetivo de esta reflexión es realizar un estudio comparativo sobre la eficacia, eficiencia técnica y costo de las tecnologías más importantes para el desarrollo de nuevos diseños vegetales, incluyendo la mejora genética, la transformación genética y ...
Pedro Martínez Gómez
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