Results 21 to 30 of about 213,096 (263)

CRISPRing into the woods [PDF]

open access: yesGM Crops & Food, 2015
The CRISPR/Cas9 technology is a welcome breakthrough for genome editing, owing to its precision, efficiency, versatility and ease of adoption. We recently reported the first application of CRISPR/Cas9 for biallelic mutations in stably transformed Populus, extending the species range of this powerful technology to woody perennials.
Tsai, Chung-Jui, Xue, Liang-Jiao
openaire   +2 more sources

Book Review: “The New Microbiology: From Microbiomes to CRISPR”

open access: yesAnnals of Clinical Microbiology, 2022
At the time when owing to COVID-19 pandemic, the public is more interested in infectious diseases and pathogens than in any other period, a book titled “The New Microbiology: From Microbiomes to CRISPR” by the renowned microbiologist Pascale Cossart was ...
Jung Oak Kang
doaj   +1 more source

Henceforth CRISPR [PDF]

open access: yesNature Biomedical Engineering, 2020
In less than a decade, the genome-editing technology now recognized by the Nobel Prize in Chemistry has impacted the biological and biomedical sciences widely. What’s next for CRISPR in biomedicine?
openaire   +2 more sources

CRISPR sabotage [PDF]

open access: yesGenome Biology, 2015
The biological arms race generally involves the rapid co-evolution of anti-virus systems in host organisms and of anti-anti-virus systems in their viral parasites. The CRISPR-Cas system is an example of a prokaryotic immune system in which such co-evolution occurs, as was recently demonstrated by the characterization of a set of viral anti-CRISPR ...
van der Oost, John, Brouns, S.J.J.
openaire   +3 more sources

A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota

open access: yesFrontiers in Microbiology, 2020
Sulfolobus islandicus codes for four DNA polymerases: three are of the B-family (Dpo1, Dpo2, and Dpo3), and one is of the Y-family (Dpo4). Western analysis revealed that among the four polymerases, only Dpo2 exhibited DNA damage-inducible expression.
Xu Feng   +7 more
doaj   +1 more source

Today's Biothreats – Where the Past Predictions Meet the Future

open access: yesВестник войск РХБ защиты, 2020
The catastrophic spread of COVID-19 pandemic, uncontrolled by modern medical science, regardless of whether it is artificial or not, clearly shows the limits of human mind and knowledge to resist this and other similar challenges.
J. Lakota
doaj   +1 more source

CRISPR decoys [PDF]

open access: yesRNA Biology, 2013
CRISPR loci consist of an array of short repeats separated by spacer sequences that match the genome of viruses and plasmids that infect prokaryotes. Transcription of the CRISPR array generates small antisense RNAs that mediate immunity against these invaders.
Inbal, Maniv   +2 more
openaire   +2 more sources

Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica

open access: yesMagna Scientia UCEVA, 2021
El objetivo de esta reflexión es realizar un estudio comparativo sobre la eficacia, eficiencia técnica y costo de las tecnologías más importantes para el desarrollo de nuevos diseños vegetales, incluyendo la mejora genética, la transformación genética y ...
Pedro Martínez Gómez
doaj   +1 more source

The Heroes of CRISPR [PDF]

open access: yesCell, 2016
Three years ago, scientists reported that CRISPR technology can enable precise and efficient genome editing in living eukaryotic cells. Since then, the method has taken the scientific community by storm, with thousands of labs using it for applications from biomedicine to agriculture.
openaire   +2 more sources

Current trends and new methods of detection of SARS-CoV-2 infection [PDF]

open access: yesCellular, Molecular and Biomedical Reports, 2022
SARS-CoV- 2 is the causative agent of the global pandemic, also known as Covid-19. This virus belongs to a group of coronaviruses and has affected more than ten million people across the globe, causing nearly half a million deaths worldwide. The pandemic
Mohammad Mohammadi   +2 more
doaj   +1 more source

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