Results 11 to 20 of about 315,823 (196)
<h2>What's Changed</h2> <ul> <li>Allow multi-condition screen design by @jykr in https://github.com/pinellolab/crispr-bean/pull/15</li> <li>v0.3.0 by @jykr in https://github.com/pinellolab/crispr-bean/pull/16</li>
Jayoung Kim Ryu, Luca Pinello
core +7 more sources
Structural studies of CRISPR-associated proteins [PDF]
, 2013 Clustered regularly interspaced short palindromic repeats (CRISPRs) act to prevent viral infection and horizontal gene transfer in prokaryotes. The genomic CRISPR array contains short sequences (“spacers”) that are derived from foreign genetic elements ...
Reeks, Judith
core +2 more sources
CRISPR: A Screener’s Guide [PDF]
SLAS Discovery, 2020 The discovery of CRISPR-Cas9 systems has fueled a rapid expansion of gene editing adoption and has impacted pharmaceutical and biotechnology research substantially. Here, gene editing is used at an industrial scale to identify and validate new biological targets for precision medicines, with functional genomic screening having an increasingly important
Carlos le Sage +2 more
openaire +3 more sources
CRISPR interference : a structural perspective [PDF]
, 2013 This article was made open access through BIS OA funding. The laboratory is funded by grants from the Biotechnology and Biological Sciences Research Council (BBSRC).CRISPR (cluster of regularly interspaced palindromic repeats) is a prokaryotic adaptive ...
Naismith, Jim +3 more
core +1 more source
CRISPRing into the woods [PDF]
GM Crops & Food, 2015 The CRISPR/Cas9 technology is a welcome breakthrough for genome editing, owing to its precision, efficiency, versatility and ease of adoption. We recently reported the first application of CRISPR/Cas9 for biallelic mutations in stably transformed Populus, extending the species range of this powerful technology to woody perennials.
Tsai, Chung-Jui, Xue, Liang-Jiao
openaire +2 more sources
Nature Biomedical Engineering, 2020 In less than a decade, the genome-editing technology now recognized by the Nobel Prize in Chemistry has impacted the biological and biomedical sciences widely. What’s next for CRISPR in biomedicine?
openaire +2 more sources
CRISPR RNA biogenesis by a Cas6 nuclease [PDF]
, 2015 Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated (Cas) proteins form the basis of a prokaryotic adaptive immune system.
Sokolowski, Richard D.
core +2 more sources
<h2>What's Changed</h2> <ul> <li>Allow multi-condition screen design by @jykr in https://github.com/pinellolab/crispr-bean/pull/15</li> <li>v0.3.0 by @jykr in https://github.com/pinellolab/crispr-bean/pull/16</li>
Jayoung Kim Ryu, Luca Pinello
core +6 more sources
Cell, 2016 Three years ago, scientists reported that CRISPR technology can enable precise and efficient genome editing in living eukaryotic cells. Since then, the method has taken the scientific community by storm, with thousands of labs using it for applications from biomedicine to agriculture.
openaire +2 more sources
Genome Biology, 2015 The biological arms race generally involves the rapid co-evolution of anti-virus systems in host organisms and of anti-anti-virus systems in their viral parasites. The CRISPR-Cas system is an example of a prokaryotic immune system in which such co-evolution occurs, as was recently demonstrated by the characterization of a set of viral anti-CRISPR ...
van der Oost, John, Brouns, S.J.J.
openaire +3 more sources