Results 191 to 200 of about 36,169 (256)

Mitochondrial Network Dynamics in Aging: Cellular Mechanisms, Intercellular Communication, and Their Impact on Tissue Adaptability. [PDF]

Int J Mol Sci
Labusca L, Gheorghevici TS, Puha B.
europepmc   +1 more source

Dental Pulp Stem Cell‐Derived Intracellular Vesicles Inhibit OSCC by Delivering PTEN to Suppress PI3K/AKT/mTOR Signalling Pathway

Cell Proliferation, EarlyView.
DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo, Qiang Qin, Wenting She, Xiangying Wang, Xiqin Li, Chenxuan Shu, Ruohan Li, Ziwei Li, Dongjie Fu, Yan He, Qingsong Ye   +10 more
wiley   +1 more source

A STAT3 degrader demonstrates efficacy in venetoclax resistant acute myeloid leukemia. [PDF]

Leukemia
Chakraborty S, Morganti C, Zaldana K, Rivera Pena B, Zhang H, Verma D, Gitego N, Ma F, Aluri S, Pradhan K, Gordon-Mitchell S, Mantzaris I, Goldfinger M, Feldman E, Gritsman K, Shi Y, Hubner S, Qiu YH, Brown BD, Khasawneh A, Skwarska A, de Camargo Magalhães ES, Verma A, Konopleva M, Tabe Y, Gavathiotis E, Colla S, Gollob J, Dey J, Kornblau SM, Koralov SB, Ito K, Shastri A.   +32 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

NEK6 Knockout Causes Defects in Mitochondrial Morphology and Respiration. [PDF]

Cells
Silva FRD, Dias PRF, Pavan ICB, Oliveira AP, Basei FL, Santos LED, Sousa LM, Consonni SR, Oliveira AG, Silveira LR, Kobarg J.   +10 more
europepmc   +1 more source

Zinc dyshomeostasis, mitochondrial dysfunction, and their pathological cycle in ischemic stroke pathophysiology: Mechanisms and potential therapeutic targets. [PDF]

Redox Biol
Liu H, Zhu Y, Geng X, Zhao H, Zhao Y.
europepmc   +1 more source

Imbalance in MICOS Proteins in Rat Liver Mitochondria in an Induced Hyperthyroidism Model. [PDF]

Cells
Venediktova N, Solomadin I, Nikiforova A, Bessonova T.   +3 more
europepmc   +1 more source

Methods to Study Mitochondrial Metabolism and Homeostasis in Fission Yeast

Yeast, EarlyView.
Ferran Gómez‐Armengol, Elena Hidalgo, Montserrat Vega   +2 more
wiley   +1 more source

Cancer cells surviving cisplatin chemotherapy increase stress-induced OMA1 activity and mitochondrial fragmentation. [PDF]

Sci Rep
Li M, McCullum CA, Rolle LTA, Ni Q, Ge Z, Sun SX, Pienta KJ, Amend SR.   +7 more
europepmc   +1 more source

Targeting mitochondrial structure and dynamics for therapeutic intervention in cancer. [PDF]

PLoS Biol
Iwata W, Haggerty N, Sesaki H, Iijima M.
europepmc   +1 more source