Results 51 to 60 of about 1,687 (191)

The Effect of an External Electric Field (EEF) on Deep Eutectic Solvent Based on Monoterpenes (V Type DESs) With Molecular Dynamics Simulation Approach

Engineering Reports, Volume 7, Issue 7, July 2025.
A deep eutectic solvent (DES) comprising menthol (MEN) as a hydrogen bond donor (HBD) and thymol (THY) as a hydrogen bond acceptor (HBA) is comprehensively investigated through COSMO‐RS and molecular dynamics (MD) simulations. COSMO‐RS is employed to predict the solid–liquid equilibrium, along with σ‐profiles and σ‐surfaces, to elucidate intermolecular
Samaneh Barani Pour, Nasrin Jabbarvand Behrooz, Jaber Jahanbin Sardroodi   +2 more
wiley   +1 more source

Developments in Diagnosis and Antileishmanial Drugs

Interdisciplinary Perspectives on Infectious Diseases, Volume 2012, Issue 1, 2012., 2012
Leishmaniasis ranks the third in disease burden in disability‐adjusted life years caused by neglected tropical diseases and is the second cause of parasite‐related deaths after malaria; but for a variety of reasons, it is not receiving the attention that would be justified seeing its importance.
Prachi Bhargava, Rajni Singh, Eliete Caló Romero   +2 more
wiley   +1 more source

In silico molecular modeling and docking studies on the leishmanial tryparedoxin peroxidase

Brazilian Archives of Biology and Technology, 2014
Leishmaniasis is one of the most common form of neglected parasitic disease that affects about 350 million people worldwide. Leishmanias have a trypanothione mediated hydroperoxide metabolism to eliminate endogenous or exogenous oxidative agents. Both of
Ozal Mutlu
doaj   +1 more source

Purple Corn Extract Prevents Doxo‐Induced Cardiotoxicity by Counteracting AMPK Activation and p53 Acetylation in HL‐1 and Primary Cardiomyocytes

Oxidative Medicine and Cellular Longevity, Volume 2025, Issue 1, 2025.
Doxorubicin (Doxo) is an anthracycline widely used as a chemotherapeutic agent for many solid and hematological cancers. Its clinical use is limited due to a cumulative dose‐dependent and irreversible cardiotoxicity that can cause progressive cardiomyopathy and congestive heart failure.
Francesca Cappellini, Debora Zorzan, Federica Tomay, Marta Toccaceli, Alessandra Marinelli, Marina Mancini, Annalisa Bucchi, Chiara Tonelli, Katia Petroni, Priya Gusain   +9 more
wiley   +1 more source

Trypanosoma cruzi Coexpressing Ornithine Decarboxylase and Green Fluorescence Proteins as a Tool to Study the Role of Polyamines in Chagas Disease Pathology

Enzyme Research, Volume 2011, Issue 1, 2011., 2011
Polyamines are essential for Trypanosoma cruzi, the causative agent of Chagas disease. As T. cruzi behaves as a natural auxotrophic organism, it relies on host polyamines biosynthesis. In this paper we obtained a double‐transfected T. cruzi parasite that expresses the green fluorescent protein (GFP) and a heterologous ornithine decarboxylase (ODC ...
Jeremías José Barclay, Luciano Gastón Morosi, María Cristina Vanrell, Edith Corina Trejo, Patricia Silvia Romano, Carolina Carrillo, Claudio Alejandro Pereira   +6 more
wiley   +1 more source

Midpoint potentials of the mitochondrial cytochromes of Crithidia fasciculata [PDF]

Journal of Bacteriology, 1976
The midpoint potentials of the mitochondrial respiratory chain cytochromes of the protozoan Crithidia fasciculata at pH 7.2, Em7.2, show great similarity to those measured in higher organisms. Values of Em7.2 for cytochromes a and a3 are +165 and +340 mV. Both c cytochromes have Em7.2 = +230 mV.
J P, Kusel, B T, Storey
openaire   +2 more sources

The Molecular Epidemiology of Crithidia Strains in Isfahan City and Surrounding Areas, Iran

مجله دانشکده پزشکی اصفهان, 2014
Background: Genotyping of Crithidia species is of high importance in the selection of an appropriate method to control and prevent cutaneous leishmaniasis (CL), determination of the best therapeutic effect of drugs, and preparation and evaluation of the ...
Monir Doudi, Mahbubeh Setorki, Gilda Eslami, Seyed Hossein Hejazi   +3 more
doaj  

Genetic analysis of clinical isolates of Leishmania major from Isfahan, Iran [PDF]

Journal of Vector Borne Diseases, 2012
Background & objectives: Leishmaniasis is a geographically widespread severe disease which includes visceralleishmaniasis (VL) and cutaneous leishmaniasis (CL).
Gilda Eslami, Rasoul Salehi, Sharifeh Khosravi & Monir Doudi
doaj  

Mutations in the Predicted Active Site of Xanthomonas oryzae pv. oryzae XopQ Differentially Affect Virulence, Suppression of Host Innate Immunity, and Induction of the HR in a Nonhost Plant

Molecular Plant-Microbe Interactions, 2015
Xanthomonas oryzae pv. oryzae, the bacterial blight pathogen of rice, secretes a number of effectors through a type 3 secretion system. One of these effectors, called XopQ, is required for virulence and suppression of rice innate immune responses induced
Mahesh Kumar Gupta, Rajkanwar Nathawat, Dipanwita Sinha, Asfarul S. Haque, Rajan Sankaranarayanan, Ramesh V. Sonti   +5 more
doaj   +1 more source

Crystallization of recombinant Crithidia fasciculata tryparedoxin

, 1999
Recombinant tryparedoxin, a thioredoxin homologue from Crithidia fasciculata, has been purified from an Escherichia coli expression system and used in crystallization trials.
Tetaud, Emmanuel, Gourley, David G., Hunter, William N., Alphey, Magnus S., Fairlamb, Alan H.; id_orcid   +4 more
core   +1 more source