Results 51 to 60 of about 4,412 (273)

Prevision of vehicle headway effect on urban traffic with a new car-following model

open access: yes, 2017
In this study, a new car-following model is established aiming to predict the variation of vehicle headways on urban road. The linear stability condition is derived corresponding to the prevision of headway in moving.
Weizhen Lu   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The influence of pre-existing vibrations on the dynamic response of medium span bridges

open access: yes, 2009
Critical static bridge loading scenarios are often expressed in terms of the number of vehicles that are present on the bridge at the time of occurrence of maximum lifetime load effect.
O'Brien, Eugene J.   +2 more
core   +1 more source

ESTIMATING AND UPDATING GAP ACCEPTANCE PARAMETERS FOR HCM6TH ROUNDABOUT CAPACITY MODEL APPLICATIONS

open access: yes, 2021
This paper treats on-field observing data and then applying estimation procedures to estimate followup headway and critical headway at roundabouts. The theory of gap acceptance constitutes the attempt to faithfully represent the behavior of users at non ...
LORENZO BROCCHINI   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modeling and Analysis on Minimum Safe Distance for Platooning Vehicles Based on Field Test of Communication Delay

open access: yesJournal of Advanced Transportation, 2021
Vehicle platooning is a perspective technique for intelligent transportation systems (ITS). Connected and automated vehicles (CAVs) use dedicated short-range communication (DSRC) to form a convoy, in which the following vehicles can receive the ...
Mengyan Hu   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Assessment dynamic ratio for traffic loading on highway bridges

open access: yes, 2011
The determination of characteristic bridge load effect is a complex problem. Usually, statistical extrapolation of simulated static load effects is used to derive a lifetime characteristic static load effect.
O\u27Brien, Eugene J.   +4 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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