Results 61 to 70 of about 4,412 (273)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Improving Driving Safety Based on Safe Distance Design in Vehicular Sensor Networks

International Journal of Distributed Sensor Networks, 2012
We proposed a Critical Safe Distance (CSD) model in V2V (Vehicle-to-Vehicle) communication systems. By elaborately analyzing the vehicular movement features for car following, we proposed a CSD definition which well balances the requirement between ...
Chen Chen, Lei Liu, Xiaobo Du, Qingqi Pei, Xiangmo Zhao   +4 more
doaj   +1 more source

Evaluation of Impacts of Adaptive Cruise Control on Mixed Traffic Flow [PDF]

This paper addresses the impacts of Adaptive (Intelligent) Cruise Control (ACC) laws on traffic flow. Semi-automated vehicles, such as ACC Vehicles, with the capability to automatically follow each other in the same lane, will coexist with manually ...
Xi Zou, David Levinson
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

That’s close enough: A threshold effect of time headway on the experience of risk, task diffculty, effort, and comfort [PDF]

, 2010
Subjective impressions of task difficulty, risk, effort, and comfort are key variables of several theories of driver behaviour. A point of difference between many of these theories is not only the importance of these variables, but also whether they are ...
Brookhuis, K.A., Lewis Evans, B., Ben Lewis-Evans, Karel A. Brookhuis, De Waard, D.; id_orcid, De Waard, D., Dick De Waard   +6 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Macroscopic Traffic Modelling on the Impact of Road Surface Potholes: Development and Numerical Solution

IEEE Access
In this paper, a second order hyperbolic traffic model is proposed to assess the impact of potholes on traffic evolution. The driver presumption to potholes considers the safe time headway, change in velocity and the changes in potholes width.
Zawar H. Khan, Ahmed B. Altamimi, Waheed Imran, Mohammad Alsaffar, Khurram S. Khattak, Fahad F. Alfaisal   +5 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Review of Roundabout Capacity Based on Gap Acceptance

Journal of Advanced Transportation, 2019
Circulating vehicles have priority at modern roundabouts. Entrance vehicles can enter the roundabout when there is a time gap larger than the critical gap; otherwise, the vehicles need to wait until there is a large enough gap.
Ruijun Guo, Leilei Liu, Wanxiang Wang
doaj   +1 more source