Results 81 to 90 of about 3,761 (238)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

DEVELOPMENT OF METHODOLOGY FOR CAPACITY CALCULATION IN THE SECTIONS WITH AN INTERMEDIATE JUNCTION

open access: yesPerner’s Contacts, 2011
This article deals with the methodology of capacity calculation in the crossing or overtaking sections with one or more junctions. The basic methodology adumbrated in (1) is developed with emphasis on thorough specification of input data and the process
Petr Veselý, Petr Krýže
doaj  

CRITICAL HEADWAY AT UNSIGNALIZED INTERSECTIONS - LITERATURE REVIEW

open access: yesINTERNATIONAL JOURNAL FOR TRAFFIC AND TRANSPORT ENGINEERING, 2021
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Critical review of the English book “New Headway-Beginner” as a curriculum for Iraqi EFL learners’ non-departmental undergraduates

open access: yesمجلة واسط للعلوم الانسانية
The suitable choice of an English coursebook for EFL learners is important to provide learners with opportunities to receive and practice the language both in and out of the classroom. This research aims to evaluate  “New Headway" textbook to determine its suitability as a curriculum in relation to the objectives of the teaching program and the ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Calibrating VISSIM roundabout model using a critical gap and follow-up headway approach

open access: yes, 2013
Roundabouts have been continuously constructed in the U.S. in recent years, as studies have shown their capability of reducing crash risk and severity when compared with signalized intersections. Despite of the safety benefits offered by roundabouts, operational efficiency is required be analyzed when considering building roundabouts.
Li, Zhixia   +4 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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