Results 11 to 20 of about 510,057 (296)
Statins in the critically ill [PDF]
Annals of Intensive Care, 2012 The use or misuse of statins in critically ill patients recently attracted the attention of intensive care clinicians. Indeed, statins are probably the most common chronic treatment before critical illness and some recent experimental and clinical data demonstrated their beneficial effects during sepsis, acute lung injury (ALI)/acute respiratory ...
De Loecker, Isabelle +1 more
openaire +3 more sources
Effectiveness of Convalescent Plasma Therapy in Treating COVID-19: an Evidence-based Case Report
Acta Medica Indonesiana, 2022 Background: Convalescent plasma is a potentially beneficial, tolerable, and available additional treatment option for COVID-19. This study aims to evaluate whether the administration of convalescent plasma therapy leads to improved clinical outcomes in ...
Mira Yulianti +5 more
doaj +2 more sources
A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage
Pathophysiology, 2021 A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed.
Eric K. Patterson +5 more
doaj +1 more source
The Intestinal Microbiome after Traumatic Injury
Microorganisms, 2023 The intestinal microbiome plays a critical role in host immune function and homeostasis. Patients suffering from—as well as models representing—multiple traumatic injuries, isolated organ system trauma, and various severities of traumatic injury have ...
Jennifer A. Munley +6 more
doaj +1 more source
Expert Consensus on the Application of Ulinastatin in Common Clinical Critical Illness [PDF]
Zhongguo quanke yixue, 2023 Ulinastatin is mainly applied in the treatment of acute pancreatitis, but also in other common clinical critical illnesses such as shock, sepsis, evere pneumonia, cute respiratory distress syndrome, several acute poisoning, severe heat stroke, severe ...
Expert group of expert consensus on the application of ulinastatin in common clinical critical illness
doaj +1 more source
Mediators of Inflammation, 2017 Sepsis is characterized by injury of the pulmonary microvasculature and the pulmonary microvascular endothelial cells (PMVEC), leading to barrier dysfunction and acute respiratory distress syndrome (ARDS).
Lefeng Wang +3 more
doaj +1 more source
Trials, 2021 Background The impact of specialist palliative care intervention in patients undergoing surgery for cancer has not been studied extensively. The SCOPE randomized controlled trial will investigate the effect of specialist palliative care intervention in ...
Onur M. Orun +7 more
doaj +1 more source
Critical Care, 2023 Background Sepsis is a heterogenous syndrome with limited therapeutic options. Identifying immunological endotypes through gene expression patterns in septic patients may lead to targeted interventions.
Jeremy A. Balch +8 more
doaj +1 more source
COVID-19 Associated Pulmonary Aspergillosis: A Case Series
Acta Medica Indonesiana, 2022 Coronavirus disease 2019 (COVID-19) has been a worldwide pandemic with several problems, one of which is the lack of definitive treatment. COVID-19-associated pulmonary aspergillosis (CAPA), the presence of invasive pulmonary aspergillosis (IPA) in COVID-
Mira Yulianti +5 more
doaj +2 more sources
Participant retention practices in longitudinal clinical research studies with high retention rates
BMC Medical Research Methodology, 2017 Background There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.
Martha Abshire +5 more
doaj +1 more source