Results 11 to 20 of about 6,679,818 (388)

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study

British medical journal, 2020
Objective To describe outcomes of people admitted to hospital with coronavirus disease 2019 (covid-19) in the United States, and the clinical and laboratory characteristics associated with severity of illness. Design Prospective cohort study.
C. Petrilli, Simon A. Jones, Jie Yang, Harish Rajagopalan, Luke O’Donnell, Yelena Chernyak, Katie A. Tobin, R. Cerfolio, F. François, Leora I. Horwitz   +9 more
semanticscholar   +1 more source

Towards definitions of critical illness and critical care using concept analysis

BMJ Open, 2022
Objective As ‘critical illness’ and ‘critical care’ lack consensus definitions, this study aimed to explore how the concepts’ are used, describe their defining attributes, and propose potential definitions. Design and methods We used the Walker and Avant
R. Kayambankadzanja,, C. Schell, Martin Gerdin Wärnberg, Thomas Tamras, Hedi Mollazadegan, M. Holmberg, H. M. Alvesson, T. Baker   +7 more
semanticscholar   +1 more source

Genetic mechanisms of critical illness in COVID-19

Nature, 2020
Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic ...
E. Pairo-Castineira, S. Clohisey, L. Klarić, A. Bretherick, K. Rawlik, D. Pasko, S. Walker, N. Parkinson, M. Fourman, C. Russell, James J Furniss, Anne Richmond, Elvina Gountouna, N. Wrobel, D. Harrison, Bo Wang, Yang Wu, A. Meynert, Fiona Griffiths, W. Oosthuyzen, A. Kousathanas, L. Moutsianas, Zhijian Yang, Ranran Zhai, Chenqing Zheng, G. Grimes, R. Beale, Jonathan E. Millar, Barbara B. Shih, Sean S. Keating, M. Zechner, C. Haley, D. Porteous, C. Hayward, Jian Yang, J. Knight, C. Summers, M. Shankar-Hari, P. Klenerman, L. Turtle, A. Ho, S. Moore, C. Hinds, P. Horby, A. Nichol, D. Maslove, L. Ling, D. McAuley, H. Montgomery, T. Walsh, Alexandre C Pereira, A. Renieri, Xia Shen, C. Ponting, A. Fawkes, A. Tenesa, M. Caulfield, Richard Scott, K. Rowan, L. Murphy, P. Openshaw, M. Semple, Andrew Law, V. Vitart, James F. Wilson, J. Baillie   +65 more
semanticscholar   +1 more source

The role of nutrition rehabilitation in the recovery of survivors of critical illness: underrecognized and underappreciated

Critical Care, 2022
Many survivors of critical illness face significant physical and psychological disability following discharge from the intensive care unit (ICU). They are often malnourished, a condition associated with poor outcomes, and nutrition remains problematic ...
L. Moisey, J. Merriweather, J. Drover
semanticscholar   +1 more source

Instruments Assessing Cognitive Impairment in Survivors of Critical Illness and Reporting of Race Norms: A Systematic Review

Critical Care Explorations, 2022
OBJECTIVE:. To conduct a systematic review to summarize cognitive instruments being used in long-term outcome studies of survivors of adult critical illness, as well as evaluate whether these measures are reported as using patient demographic norms ...
Rameela Raman, PhD, Spencer J. DesAutels, MLIS, Alana M. Lauck, MS, Alexa M. Scher, BA, Rachel L. Walden, MLIS, Amy L. Kiehl, MA, Erin M. Collar, MPH, E. Wesley Ely, MD, MPH, Pratik P. Pandharipande, MD, MSCI, James C. Jackson, PsyD   +9 more
doaj   +1 more source

Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19.

JAMA Internal Medicine, 2020
Importance Early identification of patients with novel corona virus disease 2019 (COVID-19) who may develop critical illness is of great importance and may aid in delivering proper treatment and optimizing use of resources.
W. Liang, Hengrui Liang, Limin Ou, Binfeng Chen, Ailan Chen, Caichen Li, Yimin Li, W. Guan, L. Sang, Jiatao Lu, Yuan-da Xu, Guoqiang Chen, Haiyan Guo, Jun Guo, Zisheng Chen, Yi Zhao, Shiyue Li, Nuofu Zhang, N. Zhong, Jianxing He   +19 more
semanticscholar   +1 more source

Delirium in critical illness: clinical manifestations, outcomes, and management

Intensive Care Medicine, 2021
Delirium is the most common manifestation of brain dysfunction in critically ill patients. In the intensive care unit (ICU), duration of delirium is independently predictive of excess death, length of stay, cost of care, and acquired dementia.
J. Stollings, K. Kotfis, G. Chanques, B. Pun, P. Pandharipande, E. W. Ely   +5 more
semanticscholar   +1 more source

Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic*

Critical Care Medicine, 2021
OBJECTIVE: Determine the characteristics of postintensive care syndrome in the cognitive, physical, and psychiatric domains in coronavirus disease 2019 ICU survivors. DESIGN: Single-center descriptive cohort study from April 21, to July 7, 2020. SETTING:
Miguel A. Martillo, N. Dangayach, L. Tabacof, L. Spielman, K. Dams-O’Connor, Christy C. Chan, R. Kohli-Seth, M. Cortes, M. Escalón   +8 more
semanticscholar   +1 more source

Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review

Trials, 2021
Background There is a growing number of randomized controlled trials (RCTs) evaluating interventions to prevent or treat delirium in the intensive care unit (ICU).
Elizabeth Colantuoni, Mounica Koneru, Narjes Akhlaghi, Ximin Li, Mohamed D. Hashem, Victor D. Dinglas, Karin J. Neufeld, Michael O. Harhay, Dale M. Needham   +8 more
doaj   +1 more source

Immunomodulation in the critically ill [PDF]

British Journal of Anaesthesia, 2009
Immunotherapy in the critically ill is an appealing notion because of the apparent abnormal immune and inflammatory responses seen in so many patients. The administration of a medication that could alter immune responses and decrease mortality in patients with sepsis could represent a 'magic bullet'.
Helen F. Galley, Nigel R. Webster
openaire   +3 more sources